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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum lumen | ||
| neuron projection | ||
| nucleoplasm | ||
| dendrite |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 115153213 | SALTR08100 | |||
| 115193769 | SALTR90456 | |||
| 115399016 | SALFA53909 | |||
| 115560303 | GADMO15374 | |||
| 115609680 | STRHB17565 | |||
| 116091050 | 35658_0:00103d | |||
| 116441566 | CORMO17112 | |||
| 116840008 | CHEAB19185 | |||
| 116902035 | 10117_0:00239f | |||
| 117016129 | RHIFE23329 |
