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proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule lumen | ||
| membrane | ||
| secretory granule | ||
| perikaryon | ||
| neuronal cell body |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Peptidase S8/S53 domain |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 107134363 | 9994_0:002317 | |||
| 107561970 | SINGR77016 | |||
| 108262286 | ICTPU27348 | |||
| 109319520 | CROPO06981 | |||
| 109679472 | 51338_0:0051d4 | |||
| 110208376 | PHACI01919 | |||
| 110284423 | 10089_0:0007d8 | |||
| 110317783 | 10093_0:001260 | |||
| 112922736 | VULVU15915 | |||
| 113191072 | 9999_0:00275a |
