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proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule lumen | ||
| membrane | ||
| secretory granule | ||
| perikaryon | ||
| neuronal cell body |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 102139968 | MACFA01140 | |||
| 102904462 | 230844_0:0016a1 | |||
| 103033370 | ASTMX02506 | |||
| 103115863 | ERIEU14345 | |||
| 103177907 | CALMI14435 | |||
| 103214696 | CHLSB07873 | |||
| 103256179 | CARSF29075 | |||
| 103680513 | URSMA25107 | |||
| 103747731 | 1026970_0:003a4a | NANGA20946 | ||
| 103822198 | SERCA16524 |
