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Guidelines

MIRAGE

programmed cell death 6 interacting protein

Summary

Gene Symbol

Pdcd6ip

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18571

PubChem

18571

Alliance of Genome Resources

MGI:1333753

Annotation

Keyword

Acetylation
Alternative splicing
Apoptosis
Cell division
Coiled coil
Cytoskeleton
Methylation
Phosphoprotein
Protein transport
Reference proteome
Secreted
Tight junction

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q80Y09	ALG-2-interacting protein 1
Q9WU78	ALG-2-interacting protein 1 ALG-2-interacting protein X E2F1-inducible protein Eig2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
mitotic cytokinesis	ISS
mitotic cytokinesis	ISO
mitotic cytokinesis	IBA
actomyosin contractile ring assembly	IMP	27336173
apoptotic process	TAS	10858458

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

cellular process [inference]

establishment or maintenance of cell polarity [inference]

maintenance of cell polarity [inference]

maintenance of apical/basal cell polarity [inference]

maintenance of epithelial cell apical/basal polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity [inference]

maintenance of apical/basal cell polarity [inference]

maintenance of epithelial cell apical/basal polarity

establishment or maintenance of epithelial cell apical/basal polarity [inference]

maintenance of epithelial cell apical/basal polarity

cell death [inference]

programmed cell death [inference]

apoptotic process

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

cytokinetic process [inference]

assembly of actomyosin apparatus involved in cytokinesis [inference]

actomyosin contractile ring assembly

mitotic cytokinetic process [inference]

midbody abscission

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

mitotic cell cycle process [inference]

mitotic cytokinesis

mitotic cytokinetic process [inference]

midbody abscission

actin filament-based process [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

actomyosin structure organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

actomyosin structure organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

cortical cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

cellular component assembly [inference]

assembly of actomyosin apparatus involved in cytokinesis [inference]

actomyosin contractile ring assembly

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

membrane organization [inference]

midbody abscission

cellular component biogenesis [inference]

extracellular vesicle biogenesis [inference]

extracellular exosome biogenesis

viral process [inference]

viral budding via host ESCRT complex

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

positive regulation of exosomal secretion

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of centrosome cycle [inference]

regulation of centrosome duplication

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

positive regulation of exosomal secretion

regulation of organelle assembly [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

regulation of extracellular exosome assembly

positive regulation of extracellular exosome assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

positive regulation of exosomal secretion

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

regulation of organelle assembly [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

regulation of extracellular exosome assembly

positive regulation of extracellular exosome assembly

regulation of centrosome cycle [inference]

regulation of centrosome duplication

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of extracellular exosome assembly

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of centrosome cycle [inference]

regulation of centrosome duplication

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of exosomal secretion [inference]

positive regulation of exosomal secretion

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of exosomal secretion

regulation of biological quality [inference]

regulation of membrane permeability

Displaying entries **6 - 10** of 13 in total

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GO Term	Evidence Code	PMID
melanosome	IEA
actomyosin	IDA	27336173
myelin sheath	HDA	17634366
extracellular exosome	ISO
extracellular exosome	IDA	23523921

GO Hierarchy

cellular component

cellular anatomical entity [inference]

immunological synapse

microtubule organizing center [inference]

centrosome

cytosol

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

pigment granule [inference]

melanosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

pigment granule [inference]

melanosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	15102471 19523902 19706535 20176808 22660413 25686249
SH3 domain binding	ISO
SH3 domain binding	IEA
proteinase activated receptor binding	ISO
identical protein binding	IPI	19523902

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

proteinase activated receptor binding

protein domain specific binding [inference]

SH3 domain binding

identical protein binding

protein homodimerization activity

protein dimerization activity

protein homodimerization activity

calcium-dependent protein binding

Gene Ontology information from NCBI Gene and UniProt.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026