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profilin 1

Summary

Gene Symbol

Pfn1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18643

PubChem

18643

Alliance of Genome Resources

MGI:97549

Annotation

Keyword

Acetylation
Actin-binding
Cytoskeleton
Direct protein sequencing
Isopeptide bond
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q5SX50
P62962	Profilin I
Q3U7V7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	PMID
neural tube closure	IGI	10069337
regulation of transcription by RNA polymerase II	IGI	15615774
regulation of actin polymerization or depolymerization	TAS	11274401
positive regulation of epithelial cell migration	ISO
positive regulation of epithelial cell migration	IEA

GO Hierarchy

biological process

cellular process [inference]

actin filament-based process [inference]

actin cytoskeleton organization

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

sequestering of actin monomers

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

cell junction organization [inference]

synapse organization [inference]

synapse maturation

modification of synaptic structure [inference]

modification of postsynaptic structure [inference]

modification of postsynaptic actin cytoskeleton

developmental process [inference]

developmental maturation [inference]

synapse maturation

anatomical structure formation involved in morphogenesis [inference]

tube formation [inference]

tube closure [inference]

neural tube closure

localization [inference]

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

sequestering of actin monomers

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

sequestering of actin monomers

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of viral process [inference]

positive regulation of viral transcription

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

regulation of viral process [inference]

regulation of viral transcription [inference]

positive regulation of viral transcription

positive regulation of viral process [inference]

positive regulation of viral transcription

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

regulation of cellular component biogenesis [inference]

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

regulation of protein polymerization [inference]

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

regulation of ruffle assembly [inference]

positive regulation of ruffle assembly

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

regulation of ruffle assembly [inference]

positive regulation of ruffle assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

regulation of ruffle assembly [inference]

positive regulation of ruffle assembly

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

regulation of protein polymerization [inference]

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of actin filament polymerization

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of ruffle assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament polymerization

sequestering of actin monomers

negative regulation of actin filament bundle assembly

negative regulation of stress fiber assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament polymerization

positive regulation of actin filament bundle assembly

positive regulation of stress fiber assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization

regulation of actin filament polymerization

negative regulation of actin filament polymerization

sequestering of actin monomers

positive regulation of actin filament polymerization

regulation of molecular function [inference]

regulation of ATP-dependent activity [inference]

positive regulation of ATP-dependent activity

positive regulation of molecular function [inference]

positive regulation of ATP-dependent activity

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GO Term	Evidence Code	PMID
extracellular region	TAS
nucleus	ISO
nucleus	IDA	15615774
cytoplasm	ISO
cytoplasm	IDA	11274401

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

cytoplasm

cell cortex

cytosol

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

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GO Term	Evidence Code	PMID
adenyl-nucleotide exchange factor activity	ISO
adenyl-nucleotide exchange factor activity	IEA
phosphotyrosine residue binding	ISO
phosphotyrosine residue binding	IEA
actin binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

cytoskeletal protein binding [inference]

actin binding

actin monomer binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

phosphoprotein binding [inference]

protein phosphorylated amino acid binding [inference]

phosphotyrosine residue binding

proline-rich region binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

molecular function regulator activity [inference]

ATPase regulator activity [inference]

adenyl-nucleotide exchange factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

profilin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
actin binding
actin monomer binding
sequestering of actin monomers

Displaying **all 4** entries
InterPro
Profilin conserved site
Profilin superfamily
Profilin, eukaryotic type
Profilin

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5216	Xenbase:XB-GENE-5747742	HUMAN31021
Xenopus tropicalis	18643	Xenbase:XB-GENE-5747742
Rattus norvegicus	64303		RATNO00208
Bos taurus	513895		BOVIN12661
Macaca mulatta	710753		MACMU14580
Pan troglodytes	748477		PANTR13323
Monodelphis domestica	100016522		MONDO10840
Sus scrofa	100512494		PIGXX03225
Nomascus leucogenys	100607206		NOMLE16638
Loxodonta africana	100654902		LOXAF07895

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements