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cathepsin A

Summary

Gene Symbol

Ctsa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19025

PubChem

19025

Alliance of Genome Resources

MGI:97748

Annotation

Keyword

3D-structure
Carboxypeptidase
Disulfide bond
Glycoprotein
Lysosome
Proteomics identification
Reference proteome
Signal
Zymogen

Proteins

Displaying **all 4** entries
UniProt	Protein Name
G3X8T3
P16675	Carboxypeptidase C Carboxypeptidase L Cathepsin A Protective protein cathepsin A Protective protein for beta-galactosidase
Q9D2D1
Q544R6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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2

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GO Term	Evidence Code	PMID
proteolysis	ISS
proteolysis	ISO
regulation of protein stability	ISS
regulation of protein stability	ISO
regulation of protein stability	IMP	12505983

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of biological quality [inference]

regulation of protein stability

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrion	HDA	14651853
lysosome	IEA
intracellular membrane-bounded organelle	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
serine-type carboxypeptidase activity	ISS
serine-type carboxypeptidase activity	ISO
serine-type carboxypeptidase activity	IBA
protein binding	IPI	9425240

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

serine-type carboxypeptidase activity

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

serine-type peptidase activity [inference]

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity [inference]

serine-type carboxypeptidase activity

serine-type exopeptidase activity [inference]

serine-type carboxypeptidase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

carboxypeptidase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
carboxypeptidase activity
hydrolase activity
proteolysis
serine-type carboxypeptidase activity

Displaying **all 3** entries
InterPro
Alpha/Beta hydrolase fold
Peptidase S10, serine carboxypeptidase
Serine carboxypeptidase, serine active site

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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OrthoDB (Group)

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Acknowledgements