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MIRAGE
endothelin receptor type A
Summary
- Gene Symbol
-
- EDNRA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Hypotrichosis
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P25101 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitotic cell cycle | ||
| branching involved in blood vessel morphogenesis | ||
| response to hypoxia | ||
| in utero embryonic development | ||
| blood vessel remodeling |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphatidylinositol phospholipase C activity | ||
| endothelin receptor activity | ||
| endothelin receptor activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled peptide receptor activity |
| neuropeptide receptor activity |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050848 | obstructive sleep apnea | |
| DOID:0060365 | mandibulofacial dysostosis with alopecia | |
| DOID:10763 | hypertension | |
| DOID:6364 | migraine | |
| DOID:6432 | pulmonary hypertension | |
| DOID:850 | lung disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 122217808 | PANLE27605 |
