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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Degenerin-like protein asic-1
Summary
- Gene Symbol
-
- asic-1
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- Reference proteome
- Sodium channel
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O01635 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein homotrimerization | ||
| sodium ion transport | ||
| positive regulation of dopamine secretion | ||
| ion transmembrane transport | ||
| cellular response to pH |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| sodium channel activity | ||
| ion channel activity | ||
| monoatomic ion channel activity | ||
| ligand-gated sodium channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acid-sensing ion channel, other
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ligand-gated sodium channel activity |
| monoatomic ion transport |
| sodium channel activity |
| sodium ion transmembrane transport |
| InterPro |
|---|
| Epithelial sodium channel |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050477 | Liddle syndrome | |
| DOID:0060854 | autosomal recessive pseudohypoaldosteronism type 1 | |
| DOID:0080526 | bronchiectasis 1 | |
| DOID:0080528 | bronchiectasis 3 | |
| DOID:1184 | nephrotic syndrome | |
| DOID:4479 | pseudohypoaldosteronism |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6338 | HGNC:10600 | |||
| 6339 | HGNC:10601 | |||
| 6340 | HGNC:10602 | |||
| 20278 | MGI:104695 | |||
| 24767 | RGD:3640 | |||
| 24768 | RGD:3641 | |||
| 25122 | RGD:3639 | |||
| 407667 | ZFIN:ZDB-GENE-040513-6 | |||
| 407668 | ZFIN:ZDB-GENE-040513-5 | |||
| 407669 | ZFIN:ZDB-GENE-040513-4 |
