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Peroxidasin homolog pxn-1

Summary

Gene Symbol

pxn-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

191484

PubChem

191484

Alliance of Genome Resources

WB:WBGene00004256

Annotation

Keyword

Calcium
Coiled coil
Disulfide bond
Extracellular matrix
Glycoprotein
Heme
Hydrogen peroxide
Immunoglobulin domain
Leucine-rich repeat
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q1ENI8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
response to oxidative stress	IEA
muscle attachment	IMP	25475546
hydrogen peroxide catabolic process	IEA
cellular oxidant detoxification	IEA
positive regulation of axon guidance	IMP	25475546 26194821

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

organic substance catabolic process [inference]

hydrogen peroxide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

organic substance metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

organic substance catabolic process [inference]

hydrogen peroxide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

cellular detoxification [inference]

cellular oxidant detoxification

multicellular organismal process [inference]

muscle attachment

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of axon guidance [inference]

positive regulation of axon guidance

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
basement membrane	IDA	25475546
extracellular space	IBA
extracellular matrix	IDA	25475546

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix [inference]

basement membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
peroxidase activity	IBA
peroxidase activity	IEA
heme binding	IEA
metal ion binding	IEA
lactoperoxidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on peroxide as acceptor [inference]

peroxidase activity

lactoperoxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

antioxidant activity [inference]

peroxidase activity

lactoperoxidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peroxidase

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular oxidant detoxification
heme binding
metal ion binding
oxidoreductase activity
response to oxidative stress

Displaying **all 3** entries
InterPro
Haem peroxidase domain superfamily, animal type
Haem peroxidase superfamily
Haem peroxidase, animal-type

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
extracellular matrix	PMID:25475546

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements