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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

proteinase 3

Summary

Gene Symbol

Prtn3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19152

PubChem

19152

Alliance of Genome Resources

MGI:893580

Annotation

Keyword

Cell membrane
Collagen degradation
Disulfide bond
Glycoprotein
Lysosome
Proteomics identification
Reference proteome
Secreted
Serine protease
Signal
Zymogen

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0R4IZY6
Q61096	Proteinase 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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2

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GO Term	Evidence Code	PMID
proteolysis	ISO
proteolysis	IBA
proteolysis	IEA
membrane protein ectodomain proteolysis	ISO
collagen catabolic process	IEA

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

cellular extravasation [inference]

neutrophil extravasation

myeloid leukocyte migration [inference]

granulocyte migration [inference]

neutrophil migration [inference]

neutrophil extravasation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

catabolic process [inference]

collagen catabolic process

collagen metabolic process [inference]

collagen catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

mature conventional dendritic cell differentiation

mononuclear cell differentiation [inference]

dendritic cell differentiation [inference]

mature conventional dendritic cell differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

mature conventional dendritic cell differentiation

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

cellular extravasation [inference]

neutrophil extravasation

myeloid leukocyte migration [inference]

granulocyte migration [inference]

neutrophil migration [inference]

neutrophil extravasation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

cell junction maintenance [inference]

cell-cell junction maintenance

cell-cell junction organization [inference]

cell-cell junction maintenance

cellular component maintenance [inference]

cell junction maintenance [inference]

cell-cell junction maintenance

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

mature conventional dendritic cell differentiation

mononuclear cell differentiation [inference]

dendritic cell differentiation [inference]

mature conventional dendritic cell differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

mature conventional dendritic cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of cellular process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of phagocytosis

regulation of phagocytosis [inference]

negative regulation of phagocytosis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
lysosome	IEA
cytosol	ISO
plasma membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

plasma membrane raft

membrane microdomain [inference]

plasma membrane raft

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

azurophil granule lumen

intracellular organelle lumen [inference]

vacuolar lumen [inference]

azurophil granule lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

azurophil granule lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
serine-type endopeptidase activity	ISO
serine-type endopeptidase activity	IBA
serine-type endopeptidase activity	IEA
signaling receptor binding	ISO
protein binding	IPI	25331958

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isoform A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
proteolysis
serine-type endopeptidase activity

Displaying **all 6** entries
InterPro
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026