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C-mannosyltransferase dpy-19

Summary

Gene Symbol

dpy-19

Organism

Caenorhabditis elegans

External Links

NCBI Gene

191628

KEGG Gene ID

cel:CELE_F22B7.10

PubChem

191628

Alliance of Genome Resources

WB:WBGene00001078

Annotation

Keyword

3D-structure
Developmental protein
Differentiation
Endoplasmic reticulum
Glycosyltransferase
Neurogenesis
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P34413	Protein dumpy-19

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
nervous system development	IEA
protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	IDA	23562325
cell differentiation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

peptidyl-amino acid modification [inference]

peptidyl-tryptophan modification [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

peptidyl-amino acid modification [inference]

peptidyl-tryptophan modification [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

mannosylation [inference]

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

peptidyl-amino acid modification [inference]

peptidyl-tryptophan modification [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

peptidyl-amino acid modification [inference]

peptidyl-tryptophan modification [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein C-linked glycosylation [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

protein mannosylation [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

peptidyl-amino acid modification [inference]

peptidyl-tryptophan modification [inference]

protein C-linked glycosylation via tryptophan [inference]

protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

cellular process [inference]

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
nuclear inner membrane
cytoplasm	IDA	11023868
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle inner membrane [inference]

nuclear inner membrane

nuclear membrane [inference]

nuclear inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mannosyltransferase activity	IDA	23562325
mannosyltransferase activity	IBA
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

hexosyltransferase activity [inference]

mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein, isoform A

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
mannosyltransferase activity

Displaying 1 entry
InterPro
Dpy-19/Dpy-19-like

KEGG BRITE Database

Orthology

K24553

Name

C-mannosyltransferase DPY19L [EC:2.4.1.-]

References

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
nuclear periphery	PMID:11023868 PMID:31488562

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026

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Acknowledgements