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G-protein coupled receptors family 3 profile domain-containing protein;putative metabotropic glutamate receptor mgl-1

Summary

Gene Symbol

mgl-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

191707

PubChem

191707

Alliance of Genome Resources

WB:WBGene00003232

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Glycoprotein
Receptor
Reference proteome
Signal
Transducer
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q09630
A0A0K3AWH7
A0A0K3ASV1
A3FPK2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
signal transduction	IEA
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	IEA
G protein-coupled glutamate receptor signaling pathway	IBA
positive regulation of lipid storage	IGI	18680713

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic

regulation of localization [inference]

regulation of lipid storage [inference]

positive regulation of lipid storage

regulation of lipid localization [inference]

positive regulation of lipid localization [inference]

positive regulation of lipid storage

positive regulation of biological process [inference]

positive regulation of lipid localization [inference]

positive regulation of lipid storage

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
group II metabotropic glutamate receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled glutamate receptor activity [inference]

adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [inference]

group II metabotropic glutamate receptor activity

glutamate receptor activity [inference]

G protein-coupled glutamate receptor activity [inference]

adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [inference]

group II metabotropic glutamate receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

metabotropic glutamate receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
regulation of synaptic transmission, glutamatergic

Displaying **all 6** entries
InterPro
GPCR family 3, C-terminal
GPCR, family 3, nine cysteines domain superfamily
GPCR, family 3, nine cysteines domain
GPCR, family 3
Periplasmic binding protein-like I
Receptor, ligand binding region

Ortholog

Displaying entries **1 - 10** of 20 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	2912	Xenbase:XB-GENE-1012087
Xenopus tropicalis	2913	Xenbase:XB-GENE-977445
Homo sapiens	2914	HGNC:4596
Homo sapiens	2916	HGNC:4598
Xenopus tropicalis	2917	Xenbase:XB-GENE-6036083
Homo sapiens	2918	HGNC:4600
Homo sapiens	14823	HGNC:4600
Xenopus tropicalis	24415	Xenbase:XB-GENE-1012087
Xenopus tropicalis	24416	Xenbase:XB-GENE-977445
Homo sapiens	24417	HGNC:4596