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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
serine protease 8
Summary
- Gene Symbol
-
- Prss8
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9ES87 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to mineralocorticoid | ||
| positive regulation of sodium ion transmembrane transport | ||
| positive regulation of sodium ion transport |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane | ||
| membrane raft | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| sodium channel regulator activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Peptidase S1, PA clan
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| positive regulation of sodium ion transport |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Serine proteases, trypsin domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060713 | autosomal recessive congenital ichthyosis 4B | |
| DOID:2394 | ovarian cancer | |
| DOID:3459 | breast carcinoma | |
| DOID:8634 | prostate carcinoma in situ | |
| DOID:987 | alopecia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 114052463 | VOMUR04242 | |||
| 114102913 | 93162_0:001e8f | |||
| 114582846 | PODMU01340 | |||
| 114622861 | 491861_0:001594 | |||
| 114704399 | 10041_0:0003dd | |||
| 116103045 | 35658_0:0024fa | |||
| 116891449 | 10117_0:000d82 | |||
| 117019673 | RHIFE32959 | |||
| 117707635 | 61156_0:000886 | |||
| 118578565 | 38674_0:000311 |
