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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
serine protease 8
Summary
- Gene Symbol
-
- Prss8
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9ES87 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to mineralocorticoid | ||
| positive regulation of sodium ion transmembrane transport | ||
| positive regulation of sodium ion transport |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane | ||
| membrane raft | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| sodium channel regulator activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Peptidase S1, PA clan
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| positive regulation of sodium ion transport |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Serine proteases, trypsin domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060713 | autosomal recessive congenital ichthyosis 4B | |
| DOID:2394 | ovarian cancer | |
| DOID:3459 | breast carcinoma | |
| DOID:8634 | prostate carcinoma in situ | |
| DOID:987 | alopecia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 125340381 | 214514_0:004627 | |||
| 125413569 | 447135_0:002edf | |||
| 126515938 | 100897_0:0039a6 | |||
| 127188962 | 60746_0:000d0a | |||
| 128125333 | 564181_0:0034b7 | |||
| 129691315 | 48139_1:003cd8 | |||
| 130455615 | MONDO28514 | |||
| 130880211 | 269649_0:00283b | |||
| 134470756 | CAVPO03552 |
