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MIRAGE
neuroligin 1
Summary
- Gene Symbol
-
- Nlgn1
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| retrograde trans-synaptic signaling by trans-synaptic protein complex | ||
| regulation of postsynaptic density assembly | ||
| regulation of postsynaptic density assembly | ||
| regulation of presynapse organization | ||
| maintenance of synapse structure |
GO Hierarchy
- rhythmic process
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| PDZ domain binding | ||
| signaling receptor activity | ||
| neurexin family protein binding | ||
| neurexin family protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- neuroligin
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| chemical synaptic transmission |
| modulation of chemical synaptic transmission |
| neuron cell-cell adhesion |
| postsynaptic membrane assembly |
| presynaptic membrane assembly |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase type B, conserved site |
| Carboxylesterase, type B |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder |
