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solute carrier family 9 member A5

Summary

Gene Symbol

Slc9a5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

192215

PubChem

192215

Alliance of Genome Resources

RGD:620473

Annotation

Keyword

Antiport
Cell junction
Cell membrane
Cell projection
Endosome
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Sodium transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Z0X2	Na(+)/H(+) exchanger 5 Solute carrier family 9 member 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
sodium ion transport	IDA	9933642
sodium ion transmembrane transport	ISO
sodium ion transmembrane transport	IDA	9933642
regulation of intracellular pH	ISS
regulation of intracellular pH	ISO

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of biological quality [inference]

regulation of intracellular pH

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA
focal adhesion	ISS
focal adhesion	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

recycling endosome membrane

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

dendritic spine membrane

synaptic membrane [inference]

cell junction [inference]

synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

neuron projection membrane [inference]

dendritic spine membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sodium:proton antiporter activity	ISO
sodium:proton antiporter activity	IDA	9933642
sodium:proton antiporter activity	IBA
potassium:proton antiporter activity	IBA
arrestin family protein binding	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

binding [inference]

protein binding [inference]

arrestin family protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sodium/hydrogen exchanger

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
monoatomic ion transport
potassium
regulation of intracellular pH
regulation of pH
sodium ion transmembrane transport

Displaying **all 4** entries
InterPro
Cation/H+ exchanger, CPA1 family
Cation/H+ exchanger
Na+/H+ exchanger, isoforms 3/5
Na+/H+ exchanger

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	6548	FB:FBgn0040297
Drosophila melanogaster	6549	FB:FBgn0040297
Drosophila melanogaster	6550	FB:FBgn0040297
Homo sapiens	6553	Xenbase:XB-GENE-484916	HUMAN29025
Drosophila melanogaster	20544	FB:FBgn0040297
Drosophila melanogaster	24783	FB:FBgn0040297
Drosophila melanogaster	110895	FB:FBgn0040297
Danio rerio	178126	ZFIN:ZDB-GENE-080225-43
Xenopus tropicalis	183811	Xenbase:XB-GENE-484916
Xenopus tropicalis	192215	Xenbase:XB-GENE-484916