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prolactin family 2, subfamily B, member 1

Summary

Gene Symbol

Prl2b1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

192224

PubChem

192224

Alliance of Genome Resources

RGD:620118

Annotation

Keyword

Disulfide bond
Glycoprotein
Hormone
Metal-binding
Reference proteome
Secreted
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0G2JWD1
Q9JKL9	Placental prolactin-like protein K

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation
positive regulation of lactation	IBA
cell surface receptor signaling pathway	IBA
response to nutrient levels	IBA
positive regulation of receptor signaling pathway via JAK-STAT	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway

reproductive process [inference]

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal process [inference]

multi-multicellular organism process [inference]

female pregnancy

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

mammary gland development

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of lactation

regulation of lactation [inference]

positive regulation of lactation

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of lactation

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of lactation

positive regulation of developmental process [inference]

positive regulation of lactation

positive regulation of multicellular organismal process [inference]

positive regulation of lactation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of lactation

regulation of multicellular organismal development [inference]

regulation of lactation [inference]

positive regulation of lactation

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of lactation

regulation of multicellular organismal development [inference]

regulation of lactation [inference]

positive regulation of lactation

regulation of biological quality [inference]

regulation of body fluid levels [inference]

regulation of lactation [inference]

positive regulation of lactation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
prolactin receptor binding	IBA
hormone activity	IBA IEA TAS	10471365

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

prolactin receptor binding

receptor ligand activity [inference]

hormone activity

ion binding [inference]

cation binding [inference]

metal ion binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

prolactin

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
hormone activity
positive regulation of cell population proliferation
positive regulation of lactation
prolactin receptor binding
response to nutrient levels

Displaying **all 3** entries
InterPro
Four-helical cytokine-like, core
Somatotropin hormone, conserved site
Somatotropin/prolactin

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5617			HUMAN83282
Mus musculus	66392	10090_1:003f8b	MGI:1861444	MOUSE10753
Bos taurus	280901			BOVIN19134
Sus scrofa	396965			PIGXX30868
Ovis aries	443317			SHEEP10652
Pan troglodytes	462468			PANTR37334
Canis lupus familiaris	488241			CANLF13770
Macaca mulatta	707052			MACMU35735
Felis catus	751517			FELCA11624
Danio rerio	791526		ZFIN:ZDB-GENE-030513-1