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heat shock protein family B (small) member 6

Summary

Gene Symbol

Hspb6

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

192245

PubChem

192245

Alliance of Genome Resources

RGD:621554

Annotation

Keyword

3D-structure
Chaperone
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Secreted
Stress response

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6J9Y5
P97541	Heat shock 20 kDa-like protein p20

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
chaperone-mediated protein folding	IEA ISO
positive regulation of angiogenesis	IEA ISO
protein refolding	IBA
negative regulation of apoptotic process	IBA
response to heat	IBA

GO Hierarchy

biological process

cellular process [inference]

protein folding [inference]

response to stimulus [inference]

response to stress [inference]

response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of muscle cell apoptotic process [inference]

negative regulation of striated muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of muscle cell apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of striated muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

regulation of striated muscle cell apoptotic process [inference]

negative regulation of striated muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

regulation of cardiac muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

negative regulation of apoptotic process

negative regulation of muscle cell apoptotic process [inference]

negative regulation of striated muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of muscle cell apoptotic process [inference]

negative regulation of striated muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of muscle cell apoptotic process [inference]

negative regulation of striated muscle cell apoptotic process [inference]

negative regulation of cardiac muscle cell apoptotic process

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nuclear speck	IEA ISO
extracellular region	IEA ISO
mitochondrion	IEA ISO
nucleus	IBA ISO ISS
cytosol	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

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GO Term	Evidence Code	PMID
unfolded protein binding	IBA IEA ISO

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of eye lens

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein folding chaperone

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

heat shock protein beta-6

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
protein refolding
structural constituent of eye lens
unfolded protein binding

Displaying **all 4** entries
InterPro
Alpha crystallin/Hsp20 domain
Alpha crystallin/Small heat shock protein, animal type
Alpha-crystallin, N-terminal
HSP20-like chaperone

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080093	myofibrillar myopathy 2	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB
Acomys russatus	127203898	60746_0:003227
Phodopus roborovskii	127239021	109678_0:004916
Apodemus sylvaticus	127671594	10129_0:00010e
Peromyscus californicus insignis	128125002	564181_0:00390b
Psammomys obesus	129667231	48139_1:00478d
Chionomys nivalis	130866166	269649_0:000adc
Peromyscus eremicus	131921353	42410_0:00001d

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements