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Guidelines

MIRAGE

protein tyrosine phosphatase receptor type B

Summary

Gene Symbol

Ptprb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19263

PubChem

19263

Alliance of Genome Resources

MGI:97809

Annotation

Keyword

Angiogenesis
Glycoprotein
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A1W2P7W3
B2RU80	Vascular endothelial protein tyrosine phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
angiogenesis	IDA	19451274
angiogenesis	IMP	16514057 17360632
angiogenesis	IBA
chromatin remodeling	IEA
glial cell migration	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cell motility [inference]

cell migration [inference]

glial cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
receptor complex	ISO	23382219
receptor complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity	IEA
protein binding	IPI	10557082 12234928
protein tyrosine phosphatase activity, metal-dependent	IEA
cadherin binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Receptor-type tyrosine-protein phosphatase beta

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
angiogenesis
cadherin binding

Displaying **all 4** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
PTPRJ, transmembrane domain

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5787	Xenbase:XB-GENE-991728	HUMAN14293
Xenopus tropicalis	19263	Xenbase:XB-GENE-991728
Xenopus tropicalis	32115	Xenbase:XB-GENE-991728
Xenopus tropicalis	174437	Xenbase:XB-GENE-991728
Rattus norvegicus	314843		RATNO37730
Pan troglodytes	452074		PANTR06404
Canis lupus familiaris	481162		CANLF01422
Bos taurus	505696		BOVIN29412
Caenorhabditis elegans	545902	WB:WBGene00009717
Macaca mulatta	718564		MACMU04577

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025