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Guidelines

MIRAGE

protein tyrosine phosphatase receptor type E

Summary

Gene Symbol

Ptpre

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19267

PubChem

19267

Alliance of Genome Resources

MGI:97813

Annotation

Keyword

Alternative initiation
Alternative promoter usage
Cell membrane
Cytoplasm
Glycoprotein
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3V1H5
A0A1B0GRH2
A0A1B0GRT6
P49446

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
negative regulation of insulin receptor signaling pathway	ISO
negative regulation of insulin receptor signaling pathway	IDA	18006633

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine phosphatase signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of mast cell activation

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular response to insulin stimulus [inference]

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine phosphatase signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of mast cell activation

regulation of cellular response to insulin stimulus [inference]

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of mast cell activation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	ISO
cytoplasm	ISO
cytoplasm	IDA	18006633
plasma membrane	ISO
plasma membrane	IDA	18006633

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IDA	12861030
protein tyrosine phosphatase activity	IBA
non-membrane spanning protein tyrosine phosphatase activity	IEA
protein tyrosine phosphatase activity, metal-dependent	IEA
identical protein binding	IPI	12861030

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

receptor-type tyrosine-protein phosphatase epsilon

Functional Category

L: Replication, recombination and repair
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dephosphorylation
hydrolase activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity

Displaying **all 5** entries
InterPro
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic
Protein-tyrosine phosphatase-like
Tyrosine-specific protein phosphatase, PTPase domain
Tyrosine-specific protein phosphatases domain

Ortholog

Displaying entries **81 - 84** of 84 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Scophthalmus maximus	118288096		SCOMX12735
Balaenoptera musculus	118882566		BALMU14795
Panthera leo	122201715		PANLE03179
Ursus americanus	123800048		URSAM09996

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GlyCosmos Portal v4.1.1

Last updated: February 17, 2025