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ATP-binding cassette, sub-family D member 3

Summary

Gene Symbol

Abcd3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19299

PubChem

19299

Alliance of Genome Resources

MGI:1349216

Annotation

Keyword

ATP-binding
Acetylation
Glycoprotein
Hydrolase
Peroxisome
Phosphoprotein
Reference proteome
Translocase
Transmembrane helix
Transport
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P55096	68 kDa peroxisomal membrane protein 70 kDa peroxisomal membrane protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
very long-chain fatty acid metabolic process	ISO
fatty acid biosynthetic process	ISS
fatty acid biosynthetic process	ISO
fatty acid beta-oxidation	ISO
fatty acid beta-oxidation	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process [inference]

bile acid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process

steroid biosynthetic process [inference]

bile acid biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process [inference]

bile acid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process

steroid biosynthetic process [inference]

bile acid biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

bile acid metabolic process [inference]

bile acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

organic hydroxy compound metabolic process [inference]

bile acid metabolic process [inference]

bile acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

bile acid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

bile acid metabolic process [inference]

bile acid biosynthetic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

very long-chain fatty acid catabolic process

long-chain fatty acid metabolic process [inference]

phytanic acid metabolic process

fatty acid biosynthetic process

fatty acid catabolic process [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

methyl-branched fatty acid metabolic process [inference]

phytanic acid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular lipid transport [inference]

long-chain fatty acid import into peroxisome

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

long-chain fatty acid import into peroxisome

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

peroxisome organization

response to stimulus [inference]

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to organic cyclic compound

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular lipid transport [inference]

long-chain fatty acid import into peroxisome

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

long-chain fatty acid import into peroxisome

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

organic substance transport [inference]

lipid transport

bile acid and bile salt transport

fatty acid transport [inference]

long-chain fatty acid transport [inference]

long-chain fatty acid import into peroxisome

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

intracellular lipid transport [inference]

long-chain fatty acid import into peroxisome

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

fatty acid transport [inference]

long-chain fatty acid transport [inference]

long-chain fatty acid import into peroxisome

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

carboxylic acid transmembrane transport [inference]

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

fatty acid transport [inference]

long-chain fatty acid transport [inference]

long-chain fatty acid import into peroxisome

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

carboxylic acid transmembrane transport [inference]

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

fatty acid transmembrane transport [inference]

long-chain fatty acid import into peroxisome

organic hydroxy compound transport [inference]

bile acid and bile salt transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular lipid transport [inference]

long-chain fatty acid import into peroxisome

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

long-chain fatty acid import into peroxisome

cellular localization [inference]

intracellular transport [inference]

intracellular lipid transport [inference]

long-chain fatty acid import into peroxisome

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

long-chain fatty acid import into peroxisome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	HDA	14651853 18614015
mitochondrial inner membrane	HDA	12865426
peroxisome	ISO	7772082
peroxisome	IDA	19010322 21460186 21502359 28209736 28930673

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

microbody lumen [inference]

peroxisomal matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
long-chain fatty acid transporter activity	ISS
long-chain fatty acid transporter activity	ISO
long-chain fatty acid transporter activity	IBA
protein binding	IPI	19010322
ATP binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

thiolester hydrolase activity [inference]

CoA hydrolase activity [inference]

acyl-CoA hydrolase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

long-chain fatty acid transporter activity

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-BINDING CASSETTE SUB-FAMILY D MEMBER

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ABC-type transporter activity
ATP binding
fatty acid beta-oxidation
long-chain fatty acid import into peroxisome
nucleotide binding
peroxisome organization
very long-chain fatty acid catabolic process

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111066	congenital bile acid synthesis defect 5	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	215	SGD:S000006068
Homo sapiens	5825	Xenbase:XB-GENE-983902	HUMAN50817
Saccharomyces cerevisiae S288C	11666	SGD:S000006068
Xenopus tropicalis	19299	Xenbase:XB-GENE-983902
Rattus norvegicus	25270	Xenbase:XB-GENE-983902	RATNO25225
Saccharomyces cerevisiae S288C	26874	SGD:S000006068
Saccharomyces cerevisiae S288C	84356	SGD:S000006068
Danio rerio	406803		DANRE25798
Bos taurus	526059		BOVIN26469
Macaca mulatta	709188		MACMU24835

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements