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MIRAGE

RAB22A, member RAS oncogene family

Summary

Gene Symbol

Rab22a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19334

PubChem

19334

Alliance of Genome Resources

MGI:105072

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Cytoplasmic vesicle
Endocytosis
Endosome
GTP-binding
Lipoprotein
Membrane
Nucleotide-binding
Prenylation
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P35285	Rab-14
Q0PD34

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
intracellular protein transport	IBA
endocytosis	ISO
endocytosis	IBA
endocytosis	IEA
endosome organization	IEA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

endosome organization

regulation of cellular component size [inference]

regulation of vesicle size

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

intracellular transport [inference]

intracellular protein transport

organic substance transport [inference]

protein transport

intracellular protein transport

nitrogen compound transport [inference]

protein transport

intracellular protein transport

import into cell [inference]

endocytosis

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of vesicle size

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
ruffle	IEA
early endosome	ISO
early endosome	IBA
early endosome	IEA
late endosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

endomembrane system

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

ruffle

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

endocytic vesicle [inference]

phagocytic vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

endocytic vesicle [inference]

phagocytic vesicle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

endocytic vesicle [inference]

phagocytic vesicle

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISO
GTPase activity	IDA	16034420
GTPase activity	IBA
protein binding	IPI	16034420
GTP binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RAB

Functional Category

T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying 1 entry
Gene Ontology
GTP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	19334	ZFIN:ZDB-GENE-041114-161
Homo sapiens	57403		HUMAN57647
Rattus norvegicus	366265		RATNO28120
Bos taurus	617385		BOVIN04945
Macaca mulatta	699283		MACMU01451
Pan troglodytes	736048		PANTR25233
Danio rerio	100001531		DANRE39077
Monodelphis domestica	100021761		MONDO03630
Equus caballus	100056212		HORSE20881
Sus scrofa	100144535		PIGXX12026

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Last updated: December 8, 2025