GlyCosmos Portal

Submissions

ephrin A3

Summary

Gene Symbol

EFNA3

Organism

Homo sapiens (human)

External Links

NCBI Gene

1944

PubChem

1944

Alliance of Genome Resources

HGNC:3223

JoGo

EFNA3

TogoVar

EFNA3

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
GPI-anchor
Proteomics identification
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P52797	EFL-2 EHK1 ligand EPH-related receptor tyrosine kinase ligand 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
cell-cell signaling	TAS	8660976
axon guidance	IBA
negative regulation of angiogenesis	IDA	18417479
regulation of neuron differentiation	IEA
ephrin receptor signaling pathway	ISS

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ephrin receptor signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type peptidase activity [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of amyloid precursor protein catabolic process [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type peptidase activity [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of amyloid precursor protein catabolic process [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type peptidase activity [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of amyloid precursor protein catabolic process [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

signaling [inference]

cell-cell signaling

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of amyloid precursor protein catabolic process

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

negative regulation of biological process [inference]

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of cell differentiation [inference]

regulation of neuron differentiation

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ephrin receptor signaling pathway

regulation of cell differentiation [inference]

regulation of neuron differentiation

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of hydrolase activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of peptidase activity [inference]

positive regulation of peptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of endopeptidase activity [inference]

positive regulation of endopeptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

regulation of aspartic-type peptidase activity [inference]

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

positive regulation of aspartic-type peptidase activity [inference]

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	NAS	24217950
plasma membrane	TAS	8660976
plasma membrane	IBA
side of membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
transmembrane-ephrin receptor activity	TAS	8660976
protein binding	IPI	25416956 32296183
ephrin receptor binding	IBA
ephrin receptor binding	IPI	11519828 15777695 22568954