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retinoblastoma binding protein 6, ubiquitin ligase

Summary

Gene Symbol

Rbbp6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19647

PubChem

19647

Alliance of Genome Resources

MGI:894835

Annotation

Keyword

Acetylation
Alternative splicing
Chromosome
Cytoskeleton
DNA damage
DNA replication
Isopeptide bond
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P97868	Proliferation potential-related protein Protein P2P-R RING-type E3 ubiquitin transferase RBBP6 Retinoblastoma-binding protein 6 p53-associated cellular protein of testis
A0A0R4J165

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
in utero embryonic development	IMP	17470788
DNA replication	IEA
regulation of DNA replication	ISS
regulation of DNA replication	ISO
mRNA processing	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing

mRNA metabolic process [inference]

mRNA processing

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

multicellular organism growth

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

tissue development [inference]

epithelium development [inference]

somite development

animal organ development [inference]

embryonic organ development

growth [inference]

developmental growth [inference]

multicellular organism growth

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of macromolecule metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA replication

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
chromosome	IEA
nucleolus	IEA
cytoplasm	IEA
centrosome	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

cytoplasm

microtubule organizing center [inference]

centrosome

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleic acid binding	IEA
ubiquitin-protein transferase activity	ISS
ubiquitin-protein transferase activity	ISO
zinc ion binding	IEA
protein kinase binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

e3 ubiquitin-protein ligase RBBP6

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
metal ion binding
protein ubiquitination
zinc ion binding

Displaying **all 5** entries
InterPro
DWNN domain
Zinc finger, CCHC-type superfamily
Zinc finger, CCHC-type
Zinc finger, RING/FYVE/PHD-type
Zinc knuckle CX2CX3GHX4C

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5930	Xenbase:XB-GENE-6456653	HUMAN27308
Xenopus tropicalis	19647	Xenbase:XB-GENE-6456653
Bos taurus	282034		BOVIN20472
Rattus norvegicus	308968		RATNO16102
Canis lupus familiaris	479802		CANLF16467
Macaca mulatta	701569		MACMU26583
Pan troglodytes	744733		PANTR11984
Xenopus tropicalis	853806	Xenbase:XB-GENE-6456653
Monodelphis domestica	100013429		MONDO30289
Equus caballus	100033991		HORSE07416