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EPH receptor A2

Summary

Gene Symbol

EPHA2

Organism

Homo sapiens (human)

External Links

NCBI Gene

1969

PubChem

1969

Alliance of Genome Resources

HGNC:3386

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Angiogenesis
Apoptosis
Cataract
Cell adhesion
Cell junction
Cell membrane
Cell projection
Differentiation
Disease variant
Disulfide bond
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P29317	Epithelial cell kinase Tyrosine-protein kinase receptor ECK

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 57 in total

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GO Term	Evidence Code	PMID
skeletal system development	IEA
angiogenesis	IBA
vasculogenesis	IEA
osteoblast differentiation	ISS
blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

phosphorylation [inference]

protein phosphorylation

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cellular process [inference]

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

platelet-derived growth factor receptor signaling pathway [inference]

insulin-like growth factor receptor signaling pathway

vascular endothelial growth factor receptor signaling pathway [inference]

vascular endothelial growth factor receptor-1 signaling pathway

cytokine-mediated signaling pathway [inference]

collagen-activated signaling pathway [inference]

collagen-activated tyrosine kinase receptor signaling pathway

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

cell population proliferation [inference]

epithelial cell proliferation [inference]

endothelial cell proliferation [inference]

blood vessel endothelial cell proliferation involved in sprouting angiogenesis

mammary gland epithelial cell proliferation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

phosphorylation [inference]

protein phosphorylation

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cyclic nucleotide metabolic process [inference]

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

cAMP metabolic process

cyclic purine nucleotide metabolic process [inference]

cAMP metabolic process

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

neuron differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

pericyte cell differentiation

cell development [inference]

notochord cell development

cell motility

cell migration

cell chemotaxis

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

tissue remodeling [inference]

bone remodeling

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

lens fiber cell morphogenesis

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

post-anal tail morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

formation of primary germ layer [inference]

mesoderm formation [inference]

axial mesoderm formation

notochord formation

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

neural tube development

tube development [inference]

neural tube development

cell development [inference]

notochord cell development

system development [inference]

skeletal system development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

osteoclast differentiation

neuron differentiation

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

pericyte cell differentiation

cell development [inference]

notochord cell development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to endogenous stimulus [inference]

response to growth factor

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of chemokine production [inference]

negative regulation of chemokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of chemokine production [inference]

negative regulation of chemokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of chemokine production [inference]

negative regulation of chemokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of lymphangiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis

negative regulation of angiogenesis

regulation of lymphangiogenesis [inference]

negative regulation of lymphangiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of lymphangiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

platelet-derived growth factor receptor signaling pathway [inference]

insulin-like growth factor receptor signaling pathway

vascular endothelial growth factor receptor signaling pathway [inference]

vascular endothelial growth factor receptor-1 signaling pathway

cytokine-mediated signaling pathway [inference]

collagen-activated signaling pathway [inference]

collagen-activated tyrosine kinase receptor signaling pathway

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade

regulation of cell adhesion [inference]

regulation of cell adhesion mediated by integrin

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of chemokine production [inference]

negative regulation of chemokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly

regulation of cell junction assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

regulation of bicellular tight junction assembly [inference]

positive regulation of bicellular tight junction assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly

regulation of lamellipodium organization [inference]

regulation of lamellipodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

regulation of cell junction assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of bicellular tight junction assembly

regulation of bicellular tight junction assembly [inference]

positive regulation of bicellular tight junction assembly

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

regulation of chemokine production [inference]

negative regulation of chemokine production

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

regulation of blood vessel endothelial cell migration

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of chemokine production

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	10655584 16862074 18794797 20861311
plasma membrane	IBA
focal adhesion	IDA	10655584
focal adhesion	HDA	21423176

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction

cell-substrate junction [inference]

focal adhesion

leading edge membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

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GO Term	Evidence Code	PMID
virus receptor activity	IEA
transmembrane receptor protein tyrosine kinase activity	IDA	10655584
transmembrane receptor protein tyrosine kinase activity	IBA
ephrin receptor activity
GPI-linked ephrin receptor activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

binding [inference]

protein binding

growth factor binding

cell adhesion molecule binding [inference]

cadherin binding

exogenous protein binding [inference]

virus receptor activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

ephrin receptor activity

platelet-derived growth factor receptor activity [inference]

collagen receptor activity [inference]

protein tyrosine kinase collagen receptor activity

neurotrophin receptor activity [inference]

brain-derived neurotrophic factor receptor activity

protein-hormone receptor activity [inference]

insulin receptor activity

molecular function regulator activity [inference]

molecular function activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Eph receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
ephrin receptor activity
ephrin receptor signaling pathway
nucleotide binding
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway
transmembrane-ephrin receptor activity

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InterPro
Ephrin receptor ligand binding domain
Ephrin receptor type-A /type-B
Ephrin receptor, transmembrane domain
Fibronectin type III superfamily
Fibronectin type III
Galactose-binding-like domain superfamily
Immunoglobulin-like fold
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110229	cataract 6 multiple types	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	1969	Xenbase:XB-GENE-5761259
Danio rerio	2041	ZFIN:ZDB-GENE-990415-63
Drosophila melanogaster	2042	FB:FBgn0025936
Drosophila melanogaster	2043	FB:FBgn0025936
Drosophila melanogaster	2044	FB:FBgn0025936
Drosophila melanogaster	2045	FB:FBgn0025936
Drosophila melanogaster	2046	FB:FBgn0025936
Drosophila melanogaster	2047	FB:FBgn0025936
Drosophila melanogaster	2048	FB:FBgn0025936
Drosophila melanogaster	2049	FB:FBgn0025936

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements