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RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

Rfng

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19719

KEGG Gene ID

mmu:19719

PubChem

19719

Alliance of Genome Resources

MGI:894275

Annotation

Keyword

Developmental protein
Differentiation
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Neurogenesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O09009	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
pattern specification process	IEA
positive regulation of Notch signaling pathway	IDA	15574878
positive regulation of protein binding	IDA	15574878
negative regulation of Notch signaling pathway	ISO
nervous system development	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

multicellular organismal process [inference]

pattern specification process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of binding [inference]

positive regulation of protein binding

regulation of binding [inference]

regulation of protein binding [inference]

positive regulation of protein binding

positive regulation of binding [inference]

positive regulation of protein binding

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	IBA IDA	16221665
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-1,3-N-acetylglucosaminyltransferase radical fringe

Functional Category

K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
cell differentiation
metal ion binding
nervous system development
pattern specification process
regulation of Notch signaling pathway
transferase activity

Displaying **all 2** entries
InterPro
Fringe-like, glycosyltransferase domain
Fringe

KEGG BRITE Database

Orthology

K05948

Name

fringe [EC:2.4.1.222]

References

9187150

Rhea

RHEA:70511

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.222

PMID

RHEA:70531

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.222

PMID

Ortholog

Displaying entries **41 - 50** of 89 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Castor canadensis	109702741	51338_0:000777
Sus scrofa	110255925		PIGXX01630
Mus caroli	110304960	10089_0:0035ce
Mus pahari	110331255	10093_0:00351a
Meriones unguiculatus	110548858	10047_0:0013e5
Vulpes vulpes	112920916		VULVU13628
Urocitellus parryii	113198152	9999_0:003a57
Pseudonaja textilis	113437080		PSETE08441
Electrophorus electricus	113574297		ELEEL15471
Bos indicus x Bos taurus	113877615		BOBOX14094

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements