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MIRAGE
eukaryotic translation initiation factor 4E
Summary
- Gene Symbol
-
- EIF4E
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Autism
- Chromosomal rearrangement
- Cytoplasm
- Direct protein sequencing
- Host-virus interaction
- Initiation factor
- Nucleus
- Phosphoprotein
- Proteomics identification
- RNA-binding
- Reference proteome
- Translation regulation
- mRNA transport
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G1/S transition of mitotic cell cycle | ||
| behavioral fear response | ||
| mRNA export from nucleus | ||
| translational initiation | ||
| translational initiation |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasmic stress granule | ||
| eukaryotic translation initiation factor 4F complex | ||
| eukaryotic translation initiation factor 4F complex | ||
| eukaryotic translation initiation factor 4F complex | ||
| RISC complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA cap binding | ||
| RNA 7-methylguanosine cap binding | ||
| RNA 7-methylguanosine cap binding | ||
| RNA binding | ||
| translation initiation factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- eukaryotic translation initiation factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| RNA 7-methylguanosine cap binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12849 | autistic disorder |
