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MIRAGE
ATP binding cassette subfamily A member 1
Summary
- Gene Symbol
-
- ABCA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Atherosclerosis
- Cell membrane
- Cholesterol metabolism
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Translocase
- Transmembrane helix
- Transport
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| reverse cholesterol transport | ||
| phospholipid translocation | ||
| phospholipid homeostasis | ||
| platelet dense granule organization | ||
| cellular response to lipopolysaccharide |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endosome | ||
| endoplasmic reticulum membrane | ||
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| protein binding | ||
| ATP binding | ||
| phospholipid transporter activity | ||
| high-density lipoprotein particle binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- atp-binding cassette sub-family a
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ABC-type transporter activity |
| ATP binding |
| nucleotide binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080957 | primary hypoalphalipoproteinemia 1 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1387 | hypolipoproteinemia | |
| DOID:1388 | Tangier disease | |
| DOID:3393 | coronary artery disease | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 117031810 | RHIFE21824 | ||
| 118896875 | BALMU13652 | ||
| 122204417 | PANLE26294 |
