GlyCosmos Portal

Submissions

polymerase (RNA) II (DNA directed) polypeptide A

Summary

Gene Symbol

Polr2a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20020

PubChem

20020

Alliance of Genome Resources

MGI:98086

Annotation

Keyword

Acetylation
Chromosome
Cytoplasm
DNA-binding
DNA-directed RNA polymerase
Hydrolase
Isopeptide bond
Magnesium
Metal-binding
Methylation
Nucleotidyltransferase
Nucleus
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P08775	3'-5' exoribonuclease DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit RNA-directed RNA polymerase II subunit RPB1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
transcription by RNA polymerase IV	IEA
transcription by RNA polymerase V	IEA
DNA-templated transcription termination	ISS
DNA-templated transcription termination	ISO
transcription by RNA polymerase I	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

DNA-templated transcription termination

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels

response to stimulus [inference]

response to abiotic stimulus [inference]

response to oxygen levels [inference]

cellular response to oxygen levels

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound

cellular response to chemical stimulus [inference]

cellular response to oxygen levels

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

regulation of RNA splicing [inference]

positive regulation of RNA splicing

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of RNA splicing

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA splicing

Displaying entries **1 - 5** of 13 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
euchromatin	IDA	22723415
Prp19 complex	ISS
Prp19 complex	ISO
nucleus	ISS
nucleus	ISO	14580349 16109376

GO Hierarchy

cellular component

protein-containing complex [inference]

Prp19 complex

protein-DNA complex [inference]

chromatin [inference]

euchromatin

nuclear protein-containing complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

RNA polymerase II, core complex

intracellular protein-containing complex [inference]

RNA polymerase complex [inference]

DNA-directed RNA polymerase complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

RNA polymerase II, core complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

RNA polymerase complex [inference]

DNA-directed RNA polymerase complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

RNA polymerase II, core complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying entries **1 - 5** of 17 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
magnesium ion binding	ISO
core promoter sequence-specific DNA binding	IDA	22723415
DNA binding	IDA	15601870
DNA-directed 5'-3' RNA polymerase activity	ISS
DNA-directed 5'-3' RNA polymerase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

RNA polymerase activity [inference]

5'-3' RNA polymerase activity [inference]

hydrolase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA polymerase activity [inference]

5'-3' RNA polymerase activity [inference]

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ion binding [inference]

cation binding [inference]

metal ion binding

magnesium ion binding

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

chromatin binding [inference]

promoter-specific chromatin binding

microfibril binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

core promoter sequence-specific DNA binding

DNA binding

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

core promoter sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

core promoter sequence-specific DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

DNA-directed RNA polymerase

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 2** entries
Gene Ontology
nucleotidyltransferase activity
transferase activity

Displaying **all 10** entries
InterPro
DNA-directed RNA polymerase, subunit beta-prime
RNA polymerase Rpb1, clamp domain superfamily
RNA polymerase Rpb1, domain 1
RNA polymerase Rpb1, domain 3 superfamily
RNA polymerase Rpb1, domain 3
RNA polymerase Rpb1, domain 4
RNA polymerase Rpb1, domain 5
RNA polymerase Rpb1, funnel domain superfamily
RNA polymerase, N-terminal
RNA polymerase, alpha subunit

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements