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adhesion G protein-coupled receptor E1

Summary

Gene Symbol

ADGRE1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2015

PubChem

2015

Alliance of Genome Resources

HGNC:3336

Annotation

Keyword

Adaptive immunity
Alternative splicing
Calcium
Cell membrane
Disulfide bond
EGF-like domain
G-protein coupled receptor
Glycoprotein
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A8K2Y6
A8K653
Q14246	EGF-like module receptor 1 EGF-like module-containing mucin-like hormone receptor-like 1 EMR1 hormone receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
adaptive immune response	IEA
cell adhesion	TAS	7601460
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	TAS	7601460
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

cellular process [inference]

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

response to stimulus [inference]

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
external side of plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adhesion g protein-coupled receptor l2

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

Ortholog

Displaying entries **1 - 10** of 44 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	976	Xenbase:XB-GENE-950605
Xenopus tropicalis	2015	Xenbase:XB-GENE-950605
Xenopus tropicalis	5641	Xenbase:XB-GENE-950605
Mus musculus	13733	Xenbase:XB-GENE-950605	MOUSE20427
Xenopus tropicalis	19141	Xenbase:XB-GENE-950605
Drosophila melanogaster	22859	FB:FBgn0033313
Drosophila melanogaster	23266	FB:FBgn0033313
Drosophila melanogaster	23284	FB:FBgn0033313
Xenopus tropicalis	30817	Xenbase:XB-GENE-950605
Xenopus tropicalis	32637	Xenbase:XB-GENE-950605