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SEC23 homolog A, COPII coat complex component

Summary

Gene Symbol

Sec23a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20334

PubChem

20334

Alliance of Genome Resources

MGI:1349635

Annotation

Keyword

Acetylation
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Endoplasmic reticulum
Membrane
Metal-binding
Phosphoprotein
Protein transport
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8C1E4
Q01405	SEC23-related protein A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
intracellular protein transport	TAS	11042173
protein localization to plasma membrane	IMP	27354378
COPII-coated vesicle cargo loading	ISS
COPII-coated vesicle cargo loading	ISO
COPII-coated vesicle cargo loading	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

vesicle cargo loading [inference]

COPII-coated vesicle cargo loading

intracellular transport [inference]

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

Displaying entries **6 - 10** of 13 in total

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GO Term	Evidence Code	PMID
COPII vesicle coat	ISS
COPII vesicle coat	ISO
COPII vesicle coat	IBA
COPII-coated ER to Golgi transport vesicle	IDA	21187406
perinuclear region of cytoplasm	IDA	15642376

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

vesicle coat [inference]

COPII vesicle coat

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

Displaying **all 4** entries
GO Term	Evidence Code	PMID
GTPase activator activity	IBA
protein binding	IPI	15899885 17428803 19822759 19966784
zinc ion binding	ISS
zinc ion binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SEC23

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
COPII-coated vesicle budding
COPII-coated vesicle cargo loading
metal ion binding
zinc ion binding

Displaying entries **11 - 12** of 12 in total

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InterPro
Zinc finger, Sec23/Sec24-type
von Willebrand factor A-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	10483	SGD:S000006385
Homo sapiens	10484	Xenbase:XB-GENE-999781	HUMAN19151
Xenopus tropicalis	20334	Xenbase:XB-GENE-999781
Saccharomyces cerevisiae S288C	27054	SGD:S000006385
Rattus norvegicus	58817		RATNO35314
Danio rerio	406774		DANRE12319
Pan troglodytes	452871		PANTR08625
Canis lupus familiaris	480295		CANLF17862
Bos taurus	533994		BOVIN16797
Macaca mulatta	698500		MACMU40274