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Standards Ontologies Notations
frizzled-related protein

Summary
Gene Symbol
  • Frzb
Organism
Mus musculus (house mouse)
NCBI Gene
20378
PubChem
20378
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Developmental protein
  • Differentiation
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Secreted
  • Signal
  • Wnt signaling pathway
Proteins
Displaying 1 entry
UniProt Protein Name
P97401
  • Frezzled
  • Fritz
  • Frizzled-related protein 1
  • FrzB-1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 6 - 10 of 19 in total
GO Term Evidence Code PMID
negative regulation of cell growth
inner ear morphogenesis
negative regulation of hepatocyte differentiation
somite development
negative regulation of canonical Wnt signaling pathway
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Rodentia
Group Name
secreted frizzled-related protein 3
Functional Category
  • G: Carbohydrate transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • L: Replication, recombination and repair
  • X: Mobilome: prophages, transposons
Displaying all 4 entries
Gene Ontology
Wnt-protein binding
canonical Wnt signaling pathway
cell differentiation
non-canonical Wnt signaling pathway
Displaying all 8 entries
InterPro
Frizzled cysteine-rich domain superfamily
Frizzled domain
Frizzled/secreted frizzled-related protein
Netrin domain
Netrin module, non-TIMP type
SFRP3, cysteine-rich domain
Secreted frizzled-related protein 3, NTR domain
Tissue inhibitor of metalloproteinases-like, OB-fold
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:3907 lung squamous cell carcinoma
DOID:3908 lung non-small cell carcinoma
DOID:8398 osteoarthritis
DOID:9352 type 2 diabetes mellitus
Ortholog
Displaying entries 41 - 50 of 104 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
102683261 LEPOC03082
102919080 230844_0:001aaa
103031488 ASTMX00648
103176512 CALMI10595
103217466 CHLSB01438
103659646 URSMA01289
103729866 1026970_0:000b5b NANGA07378
104657398 RHIRO18263
104871046 885580_0:003474
105289735 PTEVA08815
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024