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EPH receptor B1

Summary

Gene Symbol

EPHB1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2047

KEGG Gene ID

PubChem

2047

Alliance of Genome Resources

HGNC:3392

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell adhesion
Cell membrane
Cell projection
Direct protein sequencing
Endosome
Glycoprotein
Neurogenesis
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P54762	ELK EPH tyrosine kinase 2 EPH-like kinase 6 Neuronally-expressed EPH-related tyrosine kinase Tyrosine-protein kinase receptor EPH-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 43 in total

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GO Term	Evidence Code	PMID
skeletal muscle satellite cell activation	ISS
skeletal muscle satellite cell activation	IEA
cell migration	IEA
optic nerve morphogenesis
hindbrain tangential cell migration	IEA

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

skeletal muscle satellite cell activation

cell adhesion [inference]

cell-substrate adhesion

establishment or maintenance of cell polarity [inference]

establishment of cell polarity

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

ephrin receptor signaling pathway

cell recognition [inference]

cell-cell recognition [inference]

immunological synapse formation

metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

protein autophosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

cell population proliferation [inference]

neural precursor cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cell motility [inference]

cell migration

cell migration in hindbrain [inference]

hindbrain tangential cell migration

cell chemotaxis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis [inference]

central nervous system neuron axonogenesis [inference]

central nervous system projection neuron axonogenesis

dendritic spine morphogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendritic spine morphogenesis

neuron projection guidance [inference]

axon guidance

retinal ganglion cell axon guidance

neuron projection organization [inference]

dendritic spine organization [inference]

dendritic spine morphogenesis

postsynapse organization [inference]

dendritic spine organization [inference]

dendritic spine morphogenesis

multicellular organismal process [inference]

cell activation [inference]

skeletal muscle satellite cell activation

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

cranial nerve morphogenesis [inference]

optic nerve morphogenesis

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis [inference]

central nervous system neuron axonogenesis [inference]

central nervous system projection neuron axonogenesis

dendritic spine morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of skeletal muscle cell proliferation [inference]

negative regulation of skeletal muscle satellite cell proliferation

negative regulation of cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

regulation of skeletal muscle cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

ephrin receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of skeletal muscle cell proliferation [inference]

negative regulation of skeletal muscle satellite cell proliferation

regulation of skeletal muscle cell proliferation [inference]

regulation of skeletal muscle satellite cell proliferation [inference]

negative regulation of skeletal muscle satellite cell proliferation

negative regulation of skeletal muscle cell proliferation [inference]

negative regulation of skeletal muscle satellite cell proliferation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

regulation of skeletal muscle cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of skeletal muscle cell proliferation [inference]

negative regulation of skeletal muscle satellite cell proliferation

negative regulation of cell differentiation [inference]

negative regulation of skeletal muscle cell differentiation [inference]

negative regulation of satellite cell differentiation

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
extracellular region	TAS
cytoplasm	IEA
endoplasmic reticulum
cytosol	TAS
plasma membrane	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse [inference]

glutamatergic synapse

filopodium tip

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein kinase activity	IEA
protein tyrosine kinase activity	IEA
transmembrane receptor protein tyrosine kinase activity	IEA
ephrin receptor activity	IEA
transmembrane-ephrin receptor activity	IDA