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homeodomain interacting protein kinase 1

Summary

Gene Symbol

HIPK1

Organism

Homo sapiens (human)

External Links

NCBI Gene

204851

PubChem

204851

Alliance of Genome Resources

HGNC:19006

Annotation

Keyword

ATP-binding
Alternative splicing
Cytoplasm
Homeobox
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Transcription regulation
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q86Z02	Nuclear body-associated kinase 2
B4DZ33

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
endothelial cell apoptotic process	IDA	15701637
anterior/posterior pattern specification	IEA
protein phosphorylation	IDA	24559171
neuron differentiation	IEA
extrinsic apoptotic signaling pathway	IDA	15701637

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

epithelial cell apoptotic process [inference]

endothelial cell apoptotic process

cell population proliferation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

adherens junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

adherens junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

adherens junction assembly

adherens junction organization [inference]

adherens junction assembly

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

embryonic retina morphogenesis in camera-type eye

iris morphogenesis

developmental induction [inference]

lens induction in camera-type eye

anatomical structure formation involved in morphogenesis [inference]

retina layer formation

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

animal organ development [inference]

sensory organ development [inference]

eye development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

regulation of tumor necrosis factor-mediated signaling pathway

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleus	IBA IDA	15701637 28289210
nuclear speck	IEA
PML body	IBA
cytoplasm	IBA IDA	15701637 28289210
centrosome	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

nuclear body [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
protein serine/threonine kinase activity	IBA
protein serine kinase activity	IEA
protein tyrosine kinase activity	IBA
protein binding	IPI	12702766 25416956 28514442 32296183 33961781