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Repository for lectin-assisted multimodality data
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MIRAGE
solute carrier family 12, member 3
Summary
- Gene Symbol
-
- Slc12a3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Chloride
- Disulfide bond
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Sodium transport
- Symport
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to dietary excess |
|
|
| sodium ion transport | ||
| sodium ion transport | ||
| chloride transport | ||
| cell volume homeostasis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| plasma membrane | ||
| plasma membrane | ||
| apical plasma membrane | ||
| apical plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ATP binding | ||
| sodium:potassium:chloride symporter activity | ||
| sodium ion transmembrane transporter activity | ||
| sodium ion transmembrane transporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- solute carrier family 12 member
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell volume homeostasis |
| chloride ion homeostasis |
| chloride transmembrane transport |
| chloride |
| monoatomic ion transport |
| potassium ion homeostasis |
| InterPro |
|---|
| Amino acid permease/ SLC12A domain |
| SLC12A transporter family |
| SLC12A transporter, C-terminal |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050450 | Gitelman syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6557 | FB:FBgn0036279 | ||
| 6558 | FB:FBgn0036279 | ||
| 6559 | Xenbase:XB-GENE-866805 | HUMAN28407 | |
| 20495 | FB:FBgn0036279 | ||
| 20496 | FB:FBgn0051547 | ||
| 20497 | Xenbase:XB-GENE-866805 | ||
| 54300 | Xenbase:XB-GENE-866805 | RATNO15243 | |
| 404171 | BOVIN10489 | ||
| 415170 | FB:FBgn0036279 | ||
| 454108 | PANTR12425 |
