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solute carrier family 3, member 1

Summary

Gene Symbol

Slc3a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20532

PubChem

20532

Alliance of Genome Resources

MGI:1195264

Annotation

Keyword

Amino-acid transport
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q91WV7	D2 Neutral and basic amino acid transport protein Solute carrier family 3 member 1 b(0,+)-type amino acid transporter-related heavy chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
L-cystine transport	IDA	26739563
sucrose catabolic process
carbohydrate metabolic process	IEA
maltose catabolic process
aspartate transmembrane transport	IDA	26739563

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

maltose metabolic process [inference]

maltose catabolic process

sucrose metabolic process [inference]

sucrose catabolic process

disaccharide catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

maltose metabolic process [inference]

maltose catabolic process

sucrose metabolic process [inference]

sucrose catabolic process

disaccharide catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

disaccharide catabolic process [inference]

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport

sulfur amino acid transport [inference]

L-cystine transport

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

neutral amino acid transport [inference]

L-cystine transport

L-amino acid transport [inference]

L-cystine transport

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport

sulfur amino acid transport [inference]

L-cystine transport

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

neutral amino acid transport [inference]

L-cystine transport

L-amino acid transport [inference]

L-cystine transport

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

modified amino acid transport [inference]

L-cystine transport

nitrogen compound transport [inference]

amino acid transport

sulfur amino acid transport [inference]

L-cystine transport

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

neutral amino acid transport [inference]

L-cystine transport

L-amino acid transport [inference]

L-cystine transport

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

amide transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

modified amino acid transport [inference]

L-cystine transport

sulfur compound transport [inference]

sulfur amino acid transport [inference]

L-cystine transport

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mitochondrial inner membrane	HDA	12865426
plasma membrane	IEA
vacuolar membrane	ISO
brush border membrane	IDA ISO	12167606
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

bounding membrane of organelle [inference]

vacuolar membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
sucrose alpha-glucosidase activity
alpha-amylase activity
maltose alpha-glucosidase activity
glucan 1,4-alpha-maltotriohydrolase activity
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

beta-fructofuranosidase activity [inference]

sucrose alpha-glucosidase activity

glucosidase activity [inference]

alpha-glucosidase activity [inference]

alpha-1,4-glucosidase activity [inference]

maltose alpha-glucosidase activity

amylase activity [inference]

alpha-amylase activity

glucan 1,4-alpha-maltotriohydrolase activity

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9266	cystinuria	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **106** in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	175125	WB:WBGene00000225
Caenorhabditis elegans	178504	WB:WBGene00000224
Drosophila melanogaster	34597	FB:FBgn0032381
Drosophila melanogaster	34598	FB:FBgn0032382
Drosophila melanogaster	35824	FB:FBgn0002570
Drosophila melanogaster	35825	FB:FBgn0002569
Drosophila melanogaster	35826	FB:FBgn0002571
Drosophila melanogaster	35827	FB:FBgn0033294
Drosophila melanogaster	35828	FB:FBgn0050359
Drosophila melanogaster	35829	FB:FBgn0033296