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synaptosomal-associated protein 91

Summary

Gene Symbol

Snap91

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20616

PubChem

20616

Alliance of Genome Resources

MGI:109132

Annotation

Keyword

Alternative splicing
Cell membrane
Coated pit
Glycoprotein
Methylation
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q7TT20
Q61548	91 kDa synaptosomal-associated protein Clathrin coat-associated protein AP180 Phosphoprotein F1-20
E9Q9A3
Q3TWS4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
vesicle budding from membrane	IBA
establishment or maintenance of cell polarity	ISO
chemical synaptic transmission	IMP	11102472
neurotransmitter secretion	IMP	11102472
axonogenesis	ISO

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

establishment or maintenance of cell polarity

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular developmental process [inference]

cell development [inference]

neuron development

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

membrane organization [inference]

vesicle budding from membrane

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

anatomical structure development [inference]

cell development [inference]

neuron development

cellular developmental process [inference]

cell development [inference]

neuron development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

secretion [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

neurotransmitter secretion

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle clustering

regulation of protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of synaptic vesicle recycling [inference]

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport

regulation of synaptic vesicle clustering [inference]

positive regulation of synaptic vesicle clustering

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle clustering

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

regulation of clathrin coat assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

regulation of clathrin coat assembly [inference]

positive regulation of clathrin coat assembly

regulation of synapse organization [inference]

regulation of presynapse organization [inference]

regulation of terminal button organization

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of clathrin coat assembly

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of clathrin-dependent endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
cytosol	ISO
plasma membrane	ISO
clathrin-coated pit	IBA
synaptic vesicle	ISO
synaptic vesicle	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

AP-type membrane coat adaptor complex [inference]

clathrin adaptor complex [inference]

AP-2 adaptor complex

plasma membrane protein complex [inference]

AP-2 adaptor complex

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

synaptic membrane [inference]

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of synaptic membrane [inference]

extrinsic component of presynaptic membrane [inference]

extrinsic component of presynaptic endocytic zone membrane

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

Schaffer collateral - CA1 synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse

axon terminus

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
SNARE binding	ISO
SNARE binding	IBA
inositol hexakisphosphate binding	ISO
protein binding	IPI	10428863
1-phosphatidylinositol binding	IDA	9045662

GO Hierarchy

molecular function

binding [inference]

protein binding

SNARE binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

phospholipase binding

protein domain specific binding [inference]

SH2 domain binding

clathrin binding

clathrin heavy chain binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

1-phosphatidylinositol binding

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

small molecule binding [inference]

alcohol binding [inference]

inositol hexakisphosphate binding

ion binding [inference]

anion binding [inference]

molecular adaptor activity

protein-macromolecule adaptor activity [inference]

cargo adaptor activity [inference]

clathrin adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatidylinositol-binding clathrin assembly protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
1-phosphatidylinositol binding
SNARE binding
clathrin binding
clathrin coat assembly
clathrin heavy chain binding
clathrin-dependent endocytosis
phosphatidylinositol-4,5-bisphosphate binding
phospholipid binding
synaptic vesicle budding from presynaptic endocytic zone membrane

Displaying **all 5** entries
InterPro
ANTH domain superfamily
AP180 N-terminal homology (ANTH) domain
Clathrin coat assembly protein AP180-like
ENTH domain
ENTH/VHS

Ortholog

Displaying entries **11 - 20** of 75 in total

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Species	Gene ID	Orthologous MAtrix
Pan troglodytes	740887	PANTR38626
Equus caballus	100065464	HORSE00743
Ornithorhynchus anatinus	100076061	ORNAN10673
Pongo abelii	100173636	PONAB32145
Pongo abelii	100189926	PONAB32145
Taeniopygia guttata	100222112	TAEGU21289
Oryctolagus cuniculus	100355946	RABIT02623
Callithrix jacchus	100387455	CALJA31137
Ailuropoda melanoleuca	100465525	AILME06591
Nomascus leucogenys	100602578	NOMLE14924

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OrthoDB (Group)

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Acknowledgements