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synuclein, alpha

Summary

Gene Symbol

Snca

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20617

KEGG Gene ID

PubChem

20617

Alliance of Genome Resources

MGI:1277151

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell projection
Copper
Cytoplasm
Direct protein sequencing
Membrane
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Repeat
Secreted
Synapse
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
O55042	Non-A beta component of AD amyloid Non-A4 component of amyloid precursor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 86 in total

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GO Term	Evidence Code	PMID
microglial cell activation	IMP
positive regulation of receptor recycling	ISO
positive regulation of neurotransmitter secretion	IDA
synaptic transmission, dopaminergic	IMP
synaptic transmission, dopaminergic	IBA

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, dopaminergic

metabolic process [inference]

generation of precursor metabolites and energy [inference]

electron transport chain [inference]

respiratory electron transport chain [inference]

ATP synthesis coupled electron transport [inference]

mitochondrial ATP synthesis coupled electron transport

modified amino acid metabolic process [inference]

glutathione metabolic process

sulfur compound metabolic process [inference]

glutathione metabolic process

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process

biosynthetic process [inference]

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

dopamine biosynthetic process

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

amine biosynthetic process [inference]

biogenic amine biosynthetic process [inference]

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

dopamine biosynthetic process

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

phenol-containing compound biosynthetic process [inference]

catechol-containing compound biosynthetic process [inference]

catecholamine biosynthetic process [inference]

dopamine biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

amyloid fibril formation

primary metabolic process [inference]

lipid metabolic process [inference]

protein metabolic process [inference]

amyloid fibril formation

small molecule metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

synaptic vesicle transport

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to metal ion [inference]

cellular response to copper ion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial membrane organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

protein tetramerization

cell junction organization [inference]

synapse organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

protein tetramerization

membrane organization

mitochondrial membrane organization

supramolecular fiber organization [inference]

amyloid fibril formation

exocytic process [inference]

synaptic vesicle priming

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

synaptic vesicle exocytosis

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

behavior [inference]

locomotory behavior [inference]

adult locomotory behavior

adult behavior [inference]

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

cellular response to oxidative stress

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to fibroblast growth factor stimulus

response to fibroblast growth factor [inference]

cellular response to fibroblast growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to fibroblast growth factor stimulus

response to chemical [inference]

response to xenobiotic stimulus

response to metal ion [inference]

response to iron ion [inference]

response to iron(II) ion

response to magnesium ion

response to copper ion [inference]

cellular response to copper ion

cellular response to metal ion [inference]

cellular response to copper ion

response to lipid [inference]

response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to metal ion [inference]

cellular response to copper ion

response to peptide [inference]

response to cytokine [inference]

response to nitrogen compound [inference]

response to desipramine

response to oxygen-containing compound [inference]

response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress

cellular response to metal ion [inference]

cellular response to copper ion

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

synaptic vesicle exocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

synaptic vesicle exocytosis

synaptic vesicle transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

synaptic vesicle exocytosis

signal release [inference]

signal release from synapse [inference]

synaptic vesicle exocytosis

establishment of localization in cell [inference]

synaptic vesicle exocytosis

establishment of vesicle localization [inference]

synaptic vesicle transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

organelle localization [inference]

vesicle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

synaptic vesicle localization [inference]

synaptic vesicle transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation

regulation of signaling [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of thrombin-activated receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of platelet-derived growth factor receptor signaling pathway [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of receptor recycling

positive regulation of synaptic transmission

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

positive regulation of neurotransmitter secretion

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of long-term neuronal synaptic plasticity

long-term synaptic potentiation

positive regulation of synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, dopaminergic

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery

regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to cell periphery

regulation of transport [inference]

regulation of organic acid transport [inference]

regulation of glutamate secretion

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of secretion by cell [inference]

regulation of glutamate secretion

regulation of exocytosis [inference]

regulation of neurotransmitter secretion

positive regulation of neurotransmitter secretion

regulation of catecholamine secretion [inference]

regulation of dopamine secretion

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

positive regulation of secretion by cell [inference]

positive regulation of transport [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of endocytosis

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of norepinephrine uptake

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

positive regulation of neurotransmitter secretion

regulation of neurotransmitter uptake [inference]

negative regulation of neurotransmitter uptake [inference]

regulation of dopamine uptake involved in synaptic transmission [inference]

negative regulation of dopamine uptake involved in synaptic transmission

regulation of serotonin uptake [inference]

negative regulation of serotonin uptake

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion

regulation of norepinephrine uptake

negative regulation of norepinephrine uptake

regulation of amine transport [inference]

regulation of catecholamine secretion [inference]

regulation of dopamine secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

regulation of locomotion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of receptor recycling

positive regulation of synaptic transmission

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

positive regulation of endocytosis

positive regulation of secretion by cell [inference]

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

positive regulation of transport [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of endocytosis

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of amine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of norepinephrine uptake

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of thrombin-activated receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of platelet-derived growth factor receptor signaling pathway [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of thrombin-activated receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of platelet-derived growth factor receptor signaling pathway [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

positive regulation of neurotransmitter secretion

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of long-term neuronal synaptic plasticity

long-term synaptic potentiation

positive regulation of synaptic transmission

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of acyl-CoA biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of amine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

regulation of hydrogen peroxide catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of acyl-CoA biosynthetic process

regulation of amine metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of sulfur metabolic process [inference]

regulation of acyl-CoA biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of acyl-CoA biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling [inference]

positive regulation of receptor recycling

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of small molecule metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of acyl-CoA biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate biosynthetic process [inference]

regulation of inositol phosphate biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of acyl-CoA biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of acyl-CoA biosynthetic process

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of chaperone-mediated autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

regulation of reactive oxygen species metabolic process

regulation of hydrogen peroxide metabolic process [inference]

regulation of hydrogen peroxide catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization

regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of SNARE complex assembly [inference]

positive regulation of SNARE complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of phosphorus metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of receptor recycling

positive regulation of carbohydrate metabolic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of alcohol biosynthetic process [inference]

positive regulation of inositol phosphate biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of hydrogen peroxide catabolic process

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of release of sequestered calcium ion into cytosol

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

positive regulation of endocytosis

positive regulation of secretion by cell [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of chaperone-mediated autophagy

negative regulation of amine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of platelet-derived growth factor receptor signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of thrombin-activated receptor signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

regulation of cytoskeleton organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule cytoskeleton organization

regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

regulation of protein-containing complex assembly [inference]

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

regulation of SNARE complex assembly [inference]

positive regulation of SNARE complex assembly

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of presynapse organization [inference]

regulation of presynapse assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of microtubule polymerization or depolymerization [inference]

negative regulation of microtubule polymerization

negative regulation of protein-containing complex assembly [inference]

negative regulation of protein polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of SNARE complex assembly

positive regulation of endocytosis

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of supramolecular fiber organization [inference]

regulation of microtubule polymerization [inference]

negative regulation of microtubule polymerization

negative regulation of supramolecular fiber organization [inference]

negative regulation of microtubule polymerization

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of vesicle fusion [inference]

positive regulation of vesicle fusion [inference]

positive regulation of SNARE complex assembly

regulation of secretion by cell [inference]

regulation of glutamate secretion

regulation of exocytosis [inference]

regulation of neurotransmitter secretion

positive regulation of neurotransmitter secretion

regulation of catecholamine secretion [inference]

regulation of dopamine secretion

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

positive regulation of secretion by cell [inference]

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation

regulation of biological quality [inference]

regulation of protein stability [inference]

protein destabilization

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

excitatory postsynaptic potential

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of long-term neuronal synaptic plasticity

long-term synaptic potentiation

Displaying entries **1 - 5** of 56 in total

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GO Term	Evidence Code	PMID
extracellular region	ISS
extracellular region	ISO
extracellular region	IEA
obsolete extracellular space
nucleus	ISS

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

extracellular region

intracellular anatomical structure [inference]

inclusion body

cytoplasm

cell cortex

cytosol

membrane

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane [inference]

platelet alpha granule membrane

organelle inner membrane [inference]

mitochondrial inner membrane

nuclear membrane [inference]

nuclear outer membrane

mitochondrial membrane [inference]

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

secretory granule membrane [inference]

platelet alpha granule membrane

organelle outer membrane [inference]

cell junction [inference]

synapse

site of polarized growth [inference]

growth cone

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribosome

cytoskeleton

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membraneless organelle [inference]

ribosome

cytoskeleton

actin cytoskeleton

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

perinuclear region of cytoplasm

presynapse

postsynapse

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
SNARE binding	ISO
magnesium ion binding	ISO
actin binding	ISO
enzyme inhibitor activity	ISO
cysteine-type endopeptidase inhibitor activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

binding [inference]

protein binding

SNARE binding

cytoskeletal protein binding [inference]

actin binding

tubulin binding

enzyme binding

phospholipase binding

protein domain specific binding

heat shock protein binding [inference]

Hsp70 protein binding

protein-folding chaperone binding [inference]

Hsp70 protein binding

phosphoprotein binding

lipid binding

fatty acid binding [inference]

long-chain fatty acid binding [inference]

icosatetraenoic acid binding [inference]

arachidonate binding

phospholipid binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding [inference]

long-chain fatty acid binding [inference]

icosatetraenoic acid binding [inference]

arachidonate binding

icosanoid binding [inference]

arachidonate binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding [inference]

ferrous iron binding

copper ion binding

cuprous ion binding

zinc ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding [inference]

long-chain fatty acid binding [inference]

icosatetraenoic acid binding [inference]

arachidonate binding

icosanoid binding [inference]

arachidonate binding

protein-containing complex binding [inference]

dynein complex binding

molecular adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

enzyme activator activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

molecular function activator activity [inference]

enzyme activator activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

transporter regulator activity

molecular sequestering activity [inference]

protein sequestering activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060895	Parkinson's disease 4	Alliance of Genome Resources
DOID:0060367	Parkinson's disease 1	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	6622	HGNC:11138
Rattus norvegicus	29219	RGD:3729

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements