erb-b2 receptor tyrosine kinase 2

Summary
Gene Symbol
  • ERBB2
Organism
Homo sapiens (human)
NCBI Gene
2064
PubChem
2064
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Activator
  • Alternative initiation
  • Alternative splicing
  • Cell membrane
  • Cell projection
  • Chromosomal rearrangement
  • Cytoplasm
  • Disease variant
  • Disulfide bond
  • Endosome
  • Glycoprotein
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Signal
  • Transcription regulation
  • Transmembrane helix
  • Tyrosine-protein kinase
Proteins
Displaying all 4 entries
UniProt Protein Name
J3QLU9
F5H1T4
P04626
  • Metastatic lymph node gene 19 protein
  • Proto-oncogene Neu
  • Proto-oncogene c-ErbB-2
  • Tyrosine kinase-type cell surface receptor HER2
  • p185erbB2
X5DNK3
  • Proto-oncogene c-ErbB-2
  • p185erbB2
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 25 in total
GO Term Evidence Code PMID
semaphorin receptor complex
nucleus
nucleoplasm
cytoplasm
early endosome
GO Hierarchy
GO Hierarchy
Disease
Disease Ontology
Displaying all 9 entries
DO ID Disease Name Source
DOID:10283 prostate cancer
DOID:10534 stomach cancer
DOID:11054 urinary bladder cancer
DOID:1324 lung cancer
DOID:2394 ovarian cancer
DOID:3070 high grade glioma
DOID:3443 mammary Paget's disease
DOID:3910 lung adenocarcinoma
DOID:4450 renal cell carcinoma

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025