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AKT serine/threonine kinase 1
Summary
- Gene Symbol
-
- AKT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Disease variant
- Disulfide bond
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Isopeptide bond
- Mitochondrion
- Neurogenesis
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of glucose import | ||
| cellular response to decreased oxygen levels | ||
| positive regulation of I-kappaB phosphorylation | ||
| negative regulation of protein kinase activity | ||
| response to oxidative stress |
GO Hierarchy
- regulation of translation
- regulation of translation
- regulation of translation
- positive regulation of cell growth
- regulation of myelination
- positive regulation of cell growth
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
biological process involved in interspecies interaction between organisms [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
positive regulation of phosphorylation [inference]
regulation of kinase activity [inference]
positive regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of proteolysis [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of proteolysis [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of proteolysis [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process
regulation of signaling [inference]
regulation of signal transduction [inference]
negative regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of cellular localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cell cycle [inference]
positive regulation of protein localization [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of signaling [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
negative regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
regulation of cell communication [inference]
regulation of signal transduction [inference]
negative regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
positive regulation of phosphorylation [inference]
regulation of kinase activity [inference]
positive regulation of phosphate metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cell cycle [inference]
positive regulation of protein localization [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle [inference]
regulation of cellular localization [inference]
regulation of cell motility [inference]
regulation of molecular function [inference]
positive regulation of molecular function [inference]
regulation of catalytic activity [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| 14-3-3 protein binding | ||
| protein homodimerization activity | ||
| enzyme binding | ||
| nitric-oxide synthase regulator activity |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11054 | urinary bladder cancer | |
| DOID:1245 | vulva cancer | |
| DOID:13482 | Proteus syndrome | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0081002 | Cowden syndrome 6 | |
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:10283 | prostate cancer | |
| DOID:10763 | hypertension | |
| DOID:14330 | Parkinson's disease | |
| DOID:1574 | alcohol use disorder |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 179424 | WB:WBGene00000102 | ||
| 181524 | WB:WBGene00000103 | ||
| 41957 | FB:FBgn0010379 | ||
| 103175285 | CALMI07424 | ||
| 102359797 | LATCH20002 | ||
| 101910198 | ZFIN:ZDB-GENE-130730-1 | ||
| 103026930 | ASTMX08064 | ||
| 113571342 | ELEEL09627 | ||
| 105015651 | ESOLU44385 | ||
| 105017614 | ESOLU52845 |
