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AKT serine/threonine kinase 2
Summary
- Gene Symbol
-
- AKT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Diabetes mellitus
- Disease variant
- Disulfide bond
- Endosome
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Manganese
- Metal-binding
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| signal transduction | ||
| positive regulation of protein targeting to membrane | ||
| protein modification process | ||
| organic substance transport | ||
| glycogen biosynthetic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein serine/threonine kinase activity | ||
| protein serine kinase activity | ||
| metal ion binding | ||
| molecular function activator activity | ||
| ATP binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3069 | malignant astrocytoma | |
| DOID:3070 | high grade glioma | |
| DOID:326 | ischemia | |
| DOID:4001 | ovarian carcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity | |
| DOID:9993 | hypoglycemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 108539069 | RHIBE19124 | ||
| 104676121 | RHIRO11315 | ||
| 114603190 | PODMU31597 | ||
| 114603191 | PODMU31597 | ||
| 107557843 | SINGR67586 | ||
| 107572728 | SINGR97140 | ||
| 116833862 | CHEAB12345 | ||
| 105300159 | PTEVA04836 | ||
| 115052874 | ECHNA07345 | ||
| 115401226 | SALFA46843 |
