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AKT serine/threonine kinase 2
Summary
- Gene Symbol
-
- AKT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Diabetes mellitus
- Disease variant
- Disulfide bond
- Endosome
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Manganese
- Metal-binding
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of glucose import | ||
| positive regulation of cell motility | ||
| regulation of translation | ||
| retinal rod cell apoptotic process | ||
| protein localization to plasma membrane |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein serine/threonine kinase activity | ||
| protein serine kinase activity | ||
| metal ion binding | ||
| molecular function activator activity | ||
| ATP binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3069 | malignant astrocytoma | |
| DOID:3070 | high grade glioma | |
| DOID:326 | ischemia | |
| DOID:4001 | ovarian carcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity | |
| DOID:9993 | hypoglycemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115163684 | SALTR98858 | ||
| 115204542 | SALTR79970 | ||
| 115206563 | SALTR110608 | ||
| 115560830 | GADMO18511 | ||
| 101155451 | ORYLA03712 | ||
| 100707971 | ORENI16874 | ||
| 379783 | Xenbase:XB-GENE-484172 | ||
| 432172 | Xenbase:XB-GENE-17345542 | ||
| 100144709 | Xenbase:XB-GENE-484168 | ||
| 101946335 | CHRPI25932 |
