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steroid sulfatase

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20905

PubChem

20905

Alliance of Genome Resources

MGI:98438

Annotation

Keyword

Calcium
Disulfide bond
Glycoprotein
Hydrolase
Metal-binding
Microsome
Pregnancy
Reference proteome
Signal
Steroid metabolism
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P50427	Arylsulfatase C Steroid sulfatase Steryl-sulfate sulfohydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	ISO
steroid metabolic process	IEA
response to organic cyclic compound	ISO
response to peptide hormone	ISO
response to estrogen	ISO

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

reproductive process [inference]

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

behavior [inference]

learning or memory

multi-multicellular organism process [inference]

female pregnancy

response to stimulus [inference]

response to abiotic stimulus [inference]

response to pH

response to endogenous stimulus [inference]

response to hormone [inference]

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to organic cyclic compound

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA ISO
nuclear envelope	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

Displaying **all 4** entries
GO Term	Evidence Code	PMID
arylsulfatase activity	IBA
metal ion binding	IEA
sulfuric ester hydrolase activity	ISO	15962010
steryl-sulfatase activity	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

sulfuric ester hydrolase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

steryl-sulfatase

Functional Category

I: Lipid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
arylsulfatase activity
hydrolase activity

Displaying **all 3** entries
InterPro
Alkaline-phosphatase-like, core domain superfamily
Sulfatase, N-terminal
Sulfatase, conserved site

Rhea

RHEA:19873

H₂O + dehydroepiandrosterone 3-sulfate

H⁺ + sulfate + 3β-hydroxyandrost-5-en-17-one

Enzyme

3.1.6.2

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11383	cryptorchidism	Alliance of Genome Resources
DOID:1700	X-linked ichthyosis	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002037
Gene Name: steroid sulfatase

Ortholog

Displaying entries **21 - 30** of 48 in total

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Species	Gene ID	OrthoDB
Mus caroli	110288170	10089_0:004fe1
Mus pahari	110315743	10093_0:004fea
Urocitellus parryii	113198421	9999_0:003b0b
Cricetulus griseus	113838854	10029_0:00557f
Marmota flaviventris	114106838	93162_0:004287
Grammomys surdaster	114635806	491861_0:0032ed
Peromyscus leucopus	114689076	10041_0:00492a
Peromyscus leucopus	114689427	10041_0:00479f
Mastomys coucha	116101779	35658_0:00244c
Rattus rattus	116887839	10117_0:005395

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements