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rhodopsin

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

212541

PubChem

212541

Alliance of Genome Resources

MGI:97914

Annotation

Keyword

Acetylation
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Metal-binding
Palmitate
Phosphoprotein
Reference proteome
Retinal protein
Transmembrane helix
Vision
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P15409

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IMP	15976449
protein phosphorylation	IDA	10097103
G protein-coupled receptor signaling pathway	ISO
G protein-coupled receptor signaling pathway	IBA
visual perception	IMP	22937111

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

signal transduction [inference]

G protein-coupled receptor signaling pathway

rhodopsin mediated signaling pathway

phototransduction

light absorption [inference]

absorption of visible light

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation [inference]

rod bipolar cell differentiation

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

rhodopsin mediated signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

podosome assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

podosome assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

podosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

podosome assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus

visual perception

photoreceptor cell maintenance

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation [inference]

rod bipolar cell differentiation

locomotion [inference]

taxis [inference]

thermotaxis

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

thermotaxis

response to radiation [inference]

response to light stimulus

detection of light stimulus

phototransduction

response to light intensity

cellular response to light stimulus

rhodopsin mediated signaling pathway

cellular response to radiation [inference]

cellular response to light stimulus

rhodopsin mediated signaling pathway

detection of abiotic stimulus [inference]

detection of light stimulus

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

rhodopsin mediated signaling pathway

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of abiotic stimulus [inference]

detection of light stimulus

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

rhodopsin mediated signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

rhodopsin mediated signaling pathway

phototransduction

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	ISO	11773008 23704327
photoreceptor outer segment	IDA	10725384 12651948 20592197 21212183 22183407 22869374 23351594 23943788 25224828 26420485
photoreceptor outer segment	IBA
photoreceptor inner segment	ISO	11773008
photoreceptor inner segment	IDA	10399916

GO Hierarchy

cellular component

cellular anatomical entity [inference]

photoreceptor outer segment

rod photoreceptor outer segment

photoreceptor inner segment

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

rough endoplasmic reticulum membrane

photoreceptor disc membrane

bounding membrane of organelle [inference]

rough endoplasmic reticulum membrane

ciliary membrane [inference]

photoreceptor outer segment membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

sperm midpiece

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
11-cis retinal binding	ISS
protein binding	IPI	17881533 21307337 23746204 27509380
G protein-coupled photoreceptor activity	ISS
G protein-coupled photoreceptor activity	IBA
retinal binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

spectrin binding

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinal binding

11-cis retinal binding

small molecule binding [inference]

vitamin binding [inference]

retinal binding

11-cis retinal binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

spectrin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled photoreceptor activity

photoreceptor activity [inference]

G protein-coupled photoreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Green-sensitive opsin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular response to light stimulus
metal ion binding
photoreceptor activity
phototransduction
visual perception

Displaying **all 6** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Opsin
Rhodopsin, N-terminal
Rhodopsin
Visual pigments (opsins) retinal binding site

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110372	retinitis pigmentosa 4	Alliance of Genome Resources
DOID:0110862	congenital stationary night blindness autosomal dominant 1	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Papio anubis	101018726	PAPAN25528
Saimiri boliviensis boliviensis	101047659	SAIBB10479
Ovis aries	101123241	SHEEP08565
Gorilla gorilla gorilla	101135740	GORGO29243
Tursiops truncatus	101320374	TURTR12999
Octodon degus	101569574	OCTDE24302
Jaculus jaculus	101612324	JACJA02610
Mustela putorius furo	101671263	MUSPF19526
Heterocephalus glaber	101696995	HETGA26064
Anas platyrhynchos platyrhynchos	101793267	ANAPP10081