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retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit

Summary

Gene Symbol

Rbbp5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

213464

PubChem

213464

Alliance of Genome Resources

MGI:1918367

Annotation

Keyword

3D-structure
Alternative splicing
Chromatin regulator
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
WD repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BX09

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cellular response to DNA damage stimulus	ISO	17500065
DNA damage response	ISO	17500065
response to estrogen	ISO
response to estrogen	IEA
transcription initiation-coupled chromatin remodeling	ISO

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

transcription initiation-coupled chromatin remodeling

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to estrogen

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

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GO Term	Evidence Code	PMID
nucleus	ISO	17500065
nucleoplasm	ISO
nucleoplasm	TAS
nucleolus	ISO
nucleolus	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

histone methyltransferase complex

MLL1/2 complex

MLL1 complex

catalytic complex [inference]

transferase complex [inference]

methyltransferase complex [inference]

histone methyltransferase complex

MLL1/2 complex

MLL1 complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
transcription cis-regulatory region binding	ISO
transcription cis-regulatory region binding	IEA
protein binding	IPI	17500065 17825402 21335234 21448134 21477851 23028370 23178126 26320581
histone binding	ISO
histone binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

histone binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Retinoblastoma-binding protein 5

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Retinoblastoma-binding protein 5/Swd1
WD40 repeat
WD40/YVTN repeat-like-containing domain superfamily

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5929		HUMAN54355
Xenopus tropicalis	213464	Xenbase:XB-GENE-942063
Rattus norvegicus	304794		RATNO07039
Danio rerio	393215		DANRE22719
Pan troglodytes	457665		PANTR23468
Canis lupus familiaris	488568		CANLF14304
Bos taurus	510455		BOVIN07881
Macaca mulatta	699057		MACMU25211
Monodelphis domestica	100013956		MONDO15910
Ornithorhynchus anatinus	100076163		ORNAN25280