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parathyroid hormone 2 receptor

Summary

Gene Symbol

Pth2r

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

213527

PubChem

213527

Alliance of Genome Resources

MGI:2180917

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q91V95

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA
positive regulation of cold-induced thermogenesis	IMP	22159128

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of cold-induced thermogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IEA
parathyroid hormone receptor activity	ISO
parathyroid hormone receptor activity	IBA
G protein-coupled peptide receptor activity	IBA
peptide hormone binding	IBA

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

peptide binding [inference]

peptide hormone binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

parathyroid hormone parathyroid

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
G protein-coupled peptide receptor activity
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
cell surface receptor signaling pathway
parathyroid hormone receptor activity
peptide hormone binding

Displaying **all 6** entries
InterPro
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, parathyroid hormone receptor
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	799	WB:WBGene00015735
Caenorhabditis elegans	5745	WB:WBGene00015735
Homo sapiens	5746	Xenbase:XB-GENE-1018413	HUMAN66669
Caenorhabditis elegans	10203	WB:WBGene00015735
Caenorhabditis elegans	12311	WB:WBGene00015735
Caenorhabditis elegans	19228	WB:WBGene00015735
Caenorhabditis elegans	25029	WB:WBGene00015735
Danio rerio	30650		DANRE44717
Caenorhabditis elegans	31234	WB:WBGene00015735
Caenorhabditis elegans	54598	WB:WBGene00015735