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TAP binding protein

Summary

Gene Symbol

Tapbp

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21356

PubChem

21356

Alliance of Genome Resources

MGI:1201689

Annotation

Keyword

3D-structure
Alternative splicing
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Immunoglobulin domain
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q3U9A3	TAP-binding protein
Q9D679	TAP-binding protein
Q3TCU5	TAP-binding protein
Q8C6N4	TAP-binding protein
Q9R233	TAP-associated protein TAP-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
MHC class Ib protein complex assembly	ISO
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	IDA	9716645
peptide antigen assembly with MHC class I protein complex	ISO
peptide antigen assembly with MHC class I protein complex	IBA
defense response	IMP	10981964

GO Hierarchy

biological process

immune system process [inference]

antigen processing and presentation [inference]

antigen processing and presentation of endogenous antigen [inference]

antigen processing and presentation of endogenous peptide antigen [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I

antigen processing and presentation of exogenous antigen [inference]

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I

antigen processing and presentation of exogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

antigen processing and presentation of exogenous peptide antigen [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

antigen processing and presentation of endogenous peptide antigen [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide stabilization [inference]

peptide antigen stabilization

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide stabilization [inference]

peptide antigen stabilization

organic substance metabolic process [inference]

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide stabilization [inference]

peptide antigen stabilization

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly

MHC protein complex assembly [inference]

MHC class Ib protein complex assembly

peptide antigen assembly with MHC protein complex [inference]

peptide antigen assembly with MHC class I protein complex

protein-containing complex organization [inference]

protein-containing complex assembly

MHC protein complex assembly [inference]

MHC class Ib protein complex assembly

peptide antigen assembly with MHC protein complex [inference]

peptide antigen assembly with MHC class I protein complex

response to stimulus [inference]

response to stress [inference]

defense response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of biological quality [inference]

regulation of protein complex stability

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
Golgi membrane	ISO
endoplasmic reticulum membrane	ISO
plasma membrane	TAS	10981964
phagocytic vesicle membrane	TAS
MHC class I peptide loading complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

endoplasmic reticulum protein-containing complex [inference]

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	15187134
MHC class I protein complex binding	IBA
peptide antigen binding	TAS	12788224
protein folding chaperone	ISO
TAP1 binding	ISO

GO Hierarchy

molecular function

binding [inference]

antigen binding [inference]

peptide antigen binding

protein binding

TAP binding [inference]

amide binding [inference]

peptide binding [inference]

peptide antigen binding

protein-containing complex binding [inference]

MHC protein complex binding [inference]

MHC class I protein complex binding

TAP complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tapasin

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
MHC class I protein complex binding
TAP complex binding
peptide antigen assembly with MHC class I protein complex

Displaying **all 4** entries
InterPro
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Tapasin

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6892	Xenbase:XB-GENE-490289	HUMAN84303
Xenopus tropicalis	21356	Xenbase:XB-GENE-490289
Rattus norvegicus	25217		RATNO22567
Danio rerio	30163		DANRE15338
Canis lupus familiaris	481740		CANLF02631
Bos taurus	504335		BOVIN18284
Macaca mulatta	718235		MACMU34397
Pan troglodytes	746814		PANTR37896
Danio rerio	100034470		DANRE15381
Equus caballus	100061515		HORSE18616

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements