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poly (ADP-ribose) polymerase family, member 16

Summary

Gene Symbol

Parp16

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

214424

PubChem

214424

Alliance of Genome Resources

MGI:2446133

Annotation

Keyword

ADP-ribosylation
Endoplasmic reticulum
Glycosyltransferase
NAD
Nucleotidyltransferase
Reference proteome
Transmembrane helix
Unfolded protein response

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7TMM8	ADP-ribosyltransferase diphtheria toxin-like 15 Poly [ADP-ribose] polymerase 16

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
IRE1-mediated unfolded protein response	ISO
protein auto-ADP-ribosylation	ISO
negative regulation of cytoplasmic translation	ISO
cellular response to leukemia inhibitory factor	IEP	20439489
response to unfolded protein	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein auto-ADP-ribosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein auto-ADP-ribosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein auto-ADP-ribosylation

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein auto-ADP-ribosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein auto-ADP-ribosylation

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

response to topologically incorrect protein [inference]

response to unfolded protein

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of amide metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

regulation of cytoplasmic translation [inference]

negative regulation of cytoplasmic translation

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation [inference]

negative regulation of cytoplasmic translation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nuclear envelope	IBA ISO
endoplasmic reticulum	ISO
endoplasmic reticulum membrane
membrane	IEA
endoplasmic reticulum tubular network	IBA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle subcompartment [inference]

endoplasmic reticulum subcompartment [inference]

endoplasmic reticulum tubular network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
NAD+ ADP-ribosyltransferase activity	IBA ISO
glycosyltransferase activity	IEA
NAD+- protein-aspartate ADP-ribosyltransferase activity	ISO
NAD+-protein-glutamate ADP-ribosyltransferase activity	ISO
kinase binding	IBA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

pentosyltransferase activity [inference]

NAD+ ADP-ribosyltransferase activity

NAD+-protein ADP-ribosyltransferase activity

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

catalytic activity, acting on a protein [inference]

NAD+-protein ADP-ribosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **31 - 40** of 68 in total

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Species	Gene ID	Orthologous MAtrix
Panthera leo	122221910	PANLE20206
Balaenoptera musculus	118890979	BALMU29518
Equus caballus	100053293	HORSE15147
Sus scrofa	100512642	PIGXX14931
Bos taurus	506384	BOVIN00470
Capra hircus	102168543	CAPHI01180
Ovis aries	101119477	SHEEP17753
Oryctolagus cuniculus	100356219	RABIT05974
Dipodomys ordii	105981053	DIPOR04570
Cricetulus griseus	100753348	CRIGR16330

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