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Guidelines

MIRAGE

solute carrier family 43, member 2

Summary

Gene Symbol

Slc43a2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

215113

PubChem

215113

Alliance of Genome Resources

MGI:2442746

Annotation

Keyword

Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8CGA3	L-type amino acid transporter 4 Solute carrier family 43 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
neutral amino acid transport	IBA
L-amino acid transport	IDA	15659399
isoleucine transport	ISS
isoleucine transport	ISO
leucine transport	ISO

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

branched-chain amino acid transport [inference]

neutral amino acid transport

L-amino acid transport

L-alpha-amino acid transmembrane transport

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

branched-chain amino acid transport [inference]

neutral amino acid transport

L-amino acid transport

L-alpha-amino acid transmembrane transport

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

nitrogen compound transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

branched-chain amino acid transport [inference]

neutral amino acid transport

L-amino acid transport

L-alpha-amino acid transmembrane transport

phenylalanine transport

sulfur compound transport [inference]

sulfur amino acid transport [inference]

methionine transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

regulation of amino acid transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

negative regulation of leucine import across plasma membrane

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

negative regulation of leucine import across plasma membrane

negative regulation of transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

negative regulation of transmembrane transport [inference]

negative regulation of leucine import across plasma membrane

negative regulation of amine transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

regulation of amine transport [inference]

negative regulation of amine transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

regulation of amino acid transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

negative regulation of leucine import across plasma membrane

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of leucine import across plasma membrane

negative regulation of transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

negative regulation of transmembrane transport [inference]

negative regulation of leucine import across plasma membrane

negative regulation of amine transport [inference]

negative regulation of amino acid transport

negative regulation of leucine import across plasma membrane

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

negative regulation of leucine import across plasma membrane

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of leucine import across plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	15659399
basolateral plasma membrane	IDA	25480797 30379325

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
neutral L-amino acid transmembrane transporter activity	IBA
L-amino acid transmembrane transporter activity	IDA	15659399
L-amino acid transmembrane transporter activity	IBA
L-isoleucine transmembrane transporter activity	ISS
L-isoleucine transmembrane transporter activity	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

sulfur amino acid transmembrane transporter activity [inference]

methionine transmembrane transporter activity [inference]

L-methionine transmembrane transporter activity

aromatic amino acid transmembrane transporter activity [inference]

L-phenylalanine transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

branched-chain amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

sulfur amino acid transmembrane transporter activity [inference]

methionine transmembrane transporter activity [inference]

L-methionine transmembrane transporter activity

aromatic amino acid transmembrane transporter activity [inference]

L-phenylalanine transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

branched-chain amino acid transmembrane transporter activity [inference]

sulfur compound transmembrane transporter activity [inference]

sulfur amino acid transmembrane transporter activity [inference]

methionine transmembrane transporter activity [inference]

L-methionine transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Large neutral amino acids transporter small subunit 4

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
L-amino acid transmembrane transporter activity
neutral L-amino acid transmembrane transporter activity

Displaying **all 2** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	8501	SGD:S000004834
Saccharomyces cerevisiae S288C	29015	SGD:S000004834
Saccharomyces cerevisiae S288C	58207	SGD:S000004834
Saccharomyces cerevisiae S288C	72401	SGD:S000004834
Homo sapiens	124935	Xenbase:XB-GENE-987892	HUMAN30660
Xenopus tropicalis	215113	Xenbase:XB-GENE-987892
Rattus norvegicus	287532		RATNO01655
Canis lupus familiaris	491193		CANLF19145
Bos taurus	511955		BOVIN12497
Macaca mulatta	701666		MACMU14401

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Last updated: December 8, 2025