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coagulation factor V
Summary
- Gene Symbol
-
- F5
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Copper
- Disease variant
- Disulfide bond
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Sulfation
- Thrombophilia
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P12259 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood coagulation | ||
| blood circulation | ||
| response to vitamin K |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular space | ||
| endoplasmic reticulum lumen | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| copper ion binding | ||
| protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coagulation factor VIII
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| copper ion binding |
| oxidoreductase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050864 | non-arteritic anterior ischemic optic neuropathy | |
| DOID:0060903 | thrombosis | |
| DOID:0111902 | thrombophilia due to activated protein C resistance | |
| DOID:10003 | sensorineural hearing loss | |
| DOID:10159 | osteonecrosis | |
| DOID:10591 | pre-eclampsia | |
| DOID:11512 | Budd-Chiari syndrome | |
| DOID:1612 | breast cancer | |
| DOID:1727 | retinal vein occlusion | |
| DOID:2216 | factor V deficiency |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2153 | Xenbase:XB-GENE-987398 | ||
| 14067 | Xenbase:XB-GENE-987398 | MOUSE29245 | |
| 280687 | BOVIN08193 | ||
| 304929 | RATNO06985 | ||
| 397217 | PIGXX23532 | ||
| 445945 | TAKRU25966 | ||
| 457500 | PANTR22975 | ||
| 704695 | MACMU24087 | ||
| 100019396 | MONDO09861 | ||
| 100058503 | HORSE34101 |
